LOCUS       NC_001733              16550 bp    DNA     circular BCT 25-JAN-2008
DEFINITION  Methanocaldococcus jannaschii DSM 2661 extrachromosomal, complete
            genome.
ACCESSION   NC_001733
VERSION     NC_001733.1  GI:10954532
KEYWORDS    .
SOURCE      Methanocaldococcus jannaschii DSM 2661
  ORGANISM  Methanocaldococcus jannaschii DSM 2661
            Archaea; Euryarchaeota; Methanococci; Methanococcales;
            Methanocaldococcaceae; Methanocaldococcus.
REFERENCE   1  (bases 1 to 16550)
  AUTHORS   Bult,C.J., White,O., Olsen,G.J., Zhou,L., Fleischmann,R.D.,
            Sutton,G.G., Blake,J.A., FitzGerald,L.M., Clayton,R.A.,
            Gocayne,J.D., Kerlavage,A.R., Dougherty,B.A., Tomb,J.-F.,
            Adams,M.D., Reich,C.I., Overbeek,R., Kirkness,E.F., Weinstock,K.G.,
            Merrick,J.M., Glodek,A., Scott,J.L., Geoghagen,N.S.M.,
            Weidman,J.F., Fuhrmann,J.L., Presley,E.A., Nguyen,D.,
            Utterback,T.R., Kelley,J.M., Peterson,J.D., Sadow,P.W., Hanna,M.C.,
            Cotton,M.D., Hurst,M.A., Roberts,K.M., Kaine,B.P., Borodovsky,M.,
            Klenk,H.-P., Fraser,C.M., Smith,H.O., Woese,C.R. and Venter,J.C.
  TITLE     Complete genome sequence of the methanogenic archaeon,
            Methanococcus jannaschii
  JOURNAL   Science 273 (5278), 1058-1073 (1996)
   PUBMED   8688087
REFERENCE   2  (bases 1 to 16550)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JUN-2007) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (bases 1 to 16550)
  CONSRTM   NCBI Microbial Genomes Annotation Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JUN-2001) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from L77119.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..16550
                     /organism="Methanocaldococcus jannaschii DSM 2661"
                     /mol_type="genomic DNA"
                     /strain="DSM 2661"
                     /db_xref="taxon:243232"
                     /note="extrachromosomal
                     small extra-chromosomal element; the starts of translation
                     for some of the genes in the Methanococcus jannaschii
                     extra-chromosomal element have been extended"
     gene            complement(join(15408..16550,1..63))
                     /locus_tag="MJ_ECS12"
                     /db_xref="GeneID:1450839"
     CDS             complement(join(15408..16550,1..63))
                     /locus_tag="MJ_ECS12"
                     /codon_start=1
                     /transl_table=11
                     /product="putative transglutaminase-like protease"
                     /protein_id="NP_570910.1"
                     /db_xref="GI:18677783"
                     /db_xref="GeneID:1450839"
                     /translation="MFMNFVYIFLLLFIGVTILFIKLSHFLSIPSLKEIYSNEIKKLS
                     EQLWENSIVETLNNILEWQETNIRYWMERAADSLIYYVIAAMLYGVVLLFMVLLLIIG
                     FEIIINDIMVLILWVISAVVALLVLISLPSKYSQYLNNISMLLLVSIFTLYIFSENLI
                     IISIISGLWVLILTLIVKYLFQCNGNFVSAIAMLHDTLCYDIKVSKILKYKKAVCRDY
                     AKLTIALLSNLFPNYNLYLVTHPMHVAAAIEINGKIYVIDQRLPIREINTWIKIQSTN
                     HRILGRGYKIYKIIRKKNGFDSQKENIEKYIDKNLLNEEYIKPNWDNIIKEIYEVMKS
                     KKPNFEFELKNYAIWYDINDAIIKESLCRYIKNILRKEFCGNCSKIKDIELKQKGKDI
                     VVHLQFKLG"
     gene            complement(429..1259)
                     /locus_tag="MJECS01"
                     /db_xref="GeneID:1450828"
     CDS             complement(429..1259)
                     /locus_tag="MJECS01"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_044171.1"
                     /db_xref="GI:10954533"
                     /db_xref="GeneID:1450828"
                     /translation="MKFIFEKYYRHPINKYNGSKITPISQKNIFVVIKVELDDNELNN
                     IHDEAKKLAEDVCEKNPSGDIRTEERKLLSSFCGLIAEKVVKQLITEKLMLIKDYIEI
                     KGANVSNENFNYESHNDIEIHLSNDEIITIEIRSSIATKYDLNDILNKDFDILGSYTT
                     SYKSKEHNKDYYFRIIFHNPGDYGYNPHLKKWEYNKRLENAFKQEKNKALDYFKNNVK
                     VYFVGGCTFDDLENYGEHDDLKQKNAEYWIIRPITKGRDVLEILEILEKDILNKLGFL
                     "
     gene            complement(1269..4814)
                     /locus_tag="MJECS02"
                     /db_xref="GeneID:1450829"
     CDS             complement(1269..4814)
                     /locus_tag="MJECS02"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_044172.1"
                     /db_xref="GI:10954534"
                     /db_xref="GeneID:1450829"
                     /translation="MVVMAQTKLCSDIEIPKEVYNKWKDFIKLVGNIILSIKQIPELE
                     GKFKELLKKGRYNFKSDDFGGQLPEPFTRQKVIEPILEFLGYEFTSEISKKSPLGDRK
                     IPDYRVSVFNKEILIEAEPLGSDLNKKDSGIHQVKEWLIIKSYGVDTGIATNGLEWVL
                     LHYDDTIKEIRTLKELNLKSIFEYVLENKKDKDLENELKQVFSEFYYCFSKEYIEEYI
                     EVATKNIKHKKEEITNEFYKEFVKLVFGFEDVKDVKKKDKSSSEKDKGTKKCLYNCIE
                     APPNTSELDKKKFAVLLMNRLIFIKFLEDKGIVPRDLLRRTYEDYKKSNVLINYYDAY
                     LKPLFYEVLNTPEDERKENIRTNPYYKDIPYLNGGLFRSNNVPNELSFTIKDNEIIGE
                     VINFLERYKFTLSTSEGSEEVELNPDILGYVYEKLINILAEKGQKGLGAYYTPDEITS
                     YIAKNTIEPIVVERFKEIIKNWKINDINFSTLDEILNEDSKIAENKHILRAFLDELDK
                     IRILDPAVGSGHFLISALKELLQIKKRIYYLLREEMDIYKEKLGIILNNLYGVDIDDI
                     AVEIAKLRLWLALIENLDVEALKRGEVLLPNIEYNVRCGNSLVGWIDENLKQLSISYL
                     CDNVRIMCVLEGLIINAHNSEERKKLKKAKELLEKRDGYVLDNYVEAYHLLYEVYRTS
                     HGLKANLLKELLDEIRDSIYESVTPAYFAEIYQNGNNKKNNGKKSKKNRPRVEEFEKL
                     KPFHWKIDFGWIIKEEGFDVIIGNPPYGNLLSPTEKEIMKRRDTPEFDIFVTFIVHSS
                     KLLKNEGYLGFIIPSSFGTGVRYSNLRKELFTKMCLKKLIYLPFDVFSGAYVDNCIII
                     LHKKPPKSEDLVLIYAFPKKTKKISFEFKNDLFIEYSKILNDPKCRIFPKSPEIYIIL
                     DKIKQNCRESLTYLEDLTESTIGILASKYKFSDKKENEYYLPYLEGNVYRYETKLKLK
                     NYVDFSKHKNNEKLINLFMSPEKIFIRRIVNRQDRIMASYGNIEGVVKKDLYVFVLKP
                     DTPINYFYLLGILNSELISYIYIGKSAIALKDDFRQTTLEELRELPIVIPKNKNIINA
                     LTQLSKLRFELNDKLNENDRIFLENIIDSLVYGIYFQDLIPKEELNEICNEINGIIKK
                     YDEKSIDCLKYCQNIIKLLNTINTNELVRKIRNKN"
     gene            complement(4848..5174)
                     /locus_tag="MJECS03"
                     /db_xref="GeneID:1450830"
     CDS             complement(4848..5174)
                     /locus_tag="MJECS03"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_044173.1"
                     /db_xref="GI:10954535"
                     /db_xref="GeneID:1450830"
                     /translation="MKIIFYASREEQGFYGEAEIEEVEFFENPMKILEKYKNNLFLTE
                     EEFKKYIEDSNKKWGYGKKKKKPWIVIILKNIRKYPKVVKPKRFIPVCGKYVKEDEYE
                     QILKKL"
     gene            complement(5456..5863)
                     /locus_tag="MJECS04"
                     /db_xref="GeneID:1450831"
     CDS             complement(5456..5863)
                     /locus_tag="MJECS04"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_044174.1"
                     /db_xref="GI:10954536"
                     /db_xref="GeneID:1450831"
                     /translation="MLKKAIIKLLGIDNYIEKIEELEGERKEIFENFEKLNKKLDNFE
                     NELNFIKKEIERIQLEFNNVINSNNNDYVSKKELNDIVNQLNTLSTLVNGLIINISHG
                     NNLKESSNTVDDVKNRLLELLQSEKDYCITEIN"
     gene            6383..6817
                     /locus_tag="MJECS05"
                     /db_xref="GeneID:1450832"
     CDS             6383..6817
                     /locus_tag="MJECS05"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_044175.1"
                     /db_xref="GI:10954537"
                     /db_xref="GeneID:1450832"
                     /translation="MESKEYRKLEYNYKAFLIFSKVAMLTFLTVGIGAIFTPQTYPIM
                     PTIGFIVVAGIVSLIGMTIGALIIHQQYETLPANEKLEFKQKLLPEAYYICIELFGYG
                     SLVLLYNTFTSNNPTLCVMSLLMAGLFILVVLVIWYFGYKSY"
     gene            complement(7006..7428)
                     /locus_tag="MJECS06"
                     /db_xref="GeneID:1450833"
     CDS             complement(7006..7428)
                     /locus_tag="MJECS06"
                     /note="contains zinc finger"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_044176.1"
                     /db_xref="GI:10954538"
                     /db_xref="GeneID:1450833"
                     /translation="MNIDDYIEKLEIQKEGFFYKCPYCNYTNADVKAIKKHIKSKHYD
                     IIAKEVENLNKQNKPQRKPMKKQPKKKDDDYKDYMLLFAHKKKCKIYLDNGMIVEGTV
                     KAKDRFNIMVLDAKVDDKEVERIIIQKGHIVALIPLEE"
     gene            complement(7425..8750)
                     /locus_tag="MJECS07"
                     /db_xref="GeneID:1450834"
     CDS             complement(7425..8750)
                     /locus_tag="MJECS07"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_044177.1"
                     /db_xref="GI:10954539"
                     /db_xref="GeneID:1450834"
                     /translation="METTIMVVAMDRLTYYKLTSRYLYYFCLDRLLSCHRLDLDRDRK
                     INWRHPKYWNYNNIPKGEKPYLRHIDLWDYRGNFKDWIIENLRSIYCSPYYFESPRYE
                     LEYPAIDYNYWDWVIDIDFKGNFKKSKEIAKEVREIFKDYGVKDIHIKFSGSKGFHIW
                     INARYLPNEILNKGYVEGSTILTNFLNFKLRKLLDFVGKEGDTGIDLSIYKENMTVTA
                     PFSLYYADIEGKTPISIPFPINKVEKFKPIYLQNVKPYFIRKLTKYYENFGEIRGDLT
                     DFVDDALRYYQATKKVNNDIKIDLEINTNKKAKPKVEHSKREYIKTTIGDKEVVLNKV
                     KLESYLNELINSNWEDGKMRGCYYLTSLCKLLGYGRDKTIKLLNRWASKYGNKYIKHI
                     DYEVRYLYDRNGKVCSIKWLKENIPEAKTQIEIYKKYYELDKNNYLVKK"
     gene            complement(8735..11929)
                     /locus_tag="MJECS08"
                     /db_xref="GeneID:1450835"
     CDS             complement(8735..11929)
                     /locus_tag="MJECS08"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_044178.1"
                     /db_xref="GI:10954540"
                     /db_xref="GeneID:1450835"
                     /translation="MDKYVNGSINNIQNNNVLEYTINEINQYPEDVLEVAIKLLNIRY
                     DPNTIKELDEHNKNNTEILGNIWLFSLNKLPLKERQLLLKYGLWELGAELPTDKLYRL
                     EDAITSILGWSFWEIHDPKEVVLKLVKAGEMLHQQNRDIKIGEIVGEEFTALHQQNND
                     FTMLHQCGEEFTALHQQNNDFTMLHQLLHNIQDNSMIEDLCNKIGERANTLKKSYKND
                     DCKKTAKIFTILTFEGMRFDEFMNKAIEQLKIGEGTLKQHLKIYKQLEWIDIRKNPED
                     YDRKYIYLTYKFYEDIKDILDEYLPKKAFQEAEAKSEFMEDLKKSLKKFIEERLTPEG
                     FEFDINEVDRLKGKERIVGAYFRSLLLNEPYEAIEMIYKVYYEKYFQFKPLEINIIGL
                     ETLRSRTIMTKAKDWGEFRNKLCVFRGDIAGIIHHRKSRPILRRYVCIDLDKNGNNKG
                     CNCEVIRLYEPVENSQDYKIKCPECGRDIKYSESLFKDEDGEPIKLERDLTIAIIQLK
                     ETDEVYRVYLPYTPEINNLRDVEIVGILKTNHKGEYYIEGLSINPQKTINFNYDAFVR
                     KVKNAGYSNALDYIKDRVFYEVKAILDKEGKNPTIDTLITLEILASSHIYWDKNRDGH
                     LKPETIDCLFIGSYGQGKSLTIEPLAKLHNTTEDMIRVDMPNIENLIGLVISRDNIKF
                     YKKGIIPMNHNRPIFIEEMMDFILRVGNDLDLLKSGKTSGIWKREREGYNIPMIGVSP
                     WIGVGNIKDIDLMELWEIYHLKGFEEFKEAMINYFAKKLLKQHDYDRNEAEDRAKKIV
                     NNILGANPQLNASEWLLSKILDFTLKNLRGMTDRIPLIYLLKPYTNEDWKEIKLHTYK
                     VKRLREDNNFIKQKNLEAYECALFISYIKNKDIEFKEDALKTLWEVEEKLRDLLRDYG
                     LFKGYSDRLFNQIEYMAKAYAKLKFKEYVDLEDVRDALKIWFKTILGVLLRIKAPDKV
                     KEIFKLVGEEIKETQQKDEELEEINKLIEESRKLSQLKREILNYMLQNPKIYTTVEIA
                     ENFNISEDTARGILKELWKNGDVDNPESDQWRPL"
     gene            complement(11922..12635)
                     /locus_tag="MJECS09"
                     /db_xref="GeneID:1450836"
     CDS             complement(11922..12635)
                     /locus_tag="MJECS09"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_044179.1"
                     /db_xref="GI:10954541"
                     /db_xref="GeneID:1450836"
                     /translation="MPLPEYGTDNSDNFVRFIYFEIKKNSVKPPSFPKLGKYLENHCK
                     GGDYMCVINNYIYFLIIIDLEYLVKWIKCYSDNVLKGTIKLLTNYYSKLYYIKLSLSH
                     WLFSLCNLPLEDEMLFLSCGSLVKYQDASTHKLYKLEYLTKLILGYNRINVDNCICSI
                     KVFAISTFERFLYHEFENNAFKLIMLHKRTSFNVYKVKTSKIALLNILEKIGRTYKRY
                     LHTLKTPKNLTTTEVVRHG"
     gene            complement(13178..14038)
                     /locus_tag="MJECS10"
                     /db_xref="GeneID:1450837"
     CDS             complement(13178..14038)
                     /locus_tag="MJECS10"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_044180.1"
                     /db_xref="GI:10954542"
                     /db_xref="GeneID:1450837"
                     /translation="MNFKKVSNMPDEIICNFYVNISYLEISATYDSKNKRYSLSSKTG
                     NFNVGVKGFEKLLSIFEKIGHVMKINEKTYKIIIQNKILNLKHLYSKKNKTHTLEILD
                     EYNNLMKLSGKKLIDVALQLFKTFKINENIENSLNVKKTENDIQIINNNQNLKIEENI
                     NDSKTKENDNKCYREIIDRVLKSRSEQLFIENLENIPPKSVIYSITGAFSFIFGLGVL
                     CETLESGKIRWKAIILGFIILILILAIVNYLMMKEKNVDEHEYNIPTKLMEDVYTTDC
                     ENFPCGYFPK"
     gene            14527..15033
                     /locus_tag="MJECS11"
                     /db_xref="GeneID:1450838"
     CDS             14527..15033
                     /locus_tag="MJECS11"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_044181.2"
                     /db_xref="GI:161579527"
                     /db_xref="GeneID:1450838"
                     /translation="MLSKIERLILANQYKILKILENTSEYDEIIKILEEGYEIFYDEI
                     LGHIFDELPESEGQFVLDILSFYDIVVEPYKQKNPNDHEIINHPYSYFKGFDGNSETK
                     YMAFVRFLIEDQKKFSFVAKYAKKTDNFNSHFPMLDKYRKMVELWESKYNKKYDLKRE
                     EILDILNA"
ORIGIN      
        1 tataaatagt atagtaaccc ctataaacaa taaaaggaat atataaacaa aattcataaa
       61 caatcccttt tcaatgtttg gtttatttat agtaaagatt taatatcctc gtattattct
      121 acaccccatt ttcaataatc ctaacccact catgagatat tattttctta attaatttgt
      181 ttatttcttt atcacctttt attgattcat aaacttcatt aattgttttt agattttctt
      241 cctctaattg ttttaattcc tcttcctctt cttctgttaa atcgccttct aacagctttt
      301 tccaatacaa ttcagcccat ctatcataat ttattggttt taagtgcttt gaaattgttt
      361 ctaatagatg ttcttcatcc ccactgtata attttgtttg gagcggagct tttaaggaac
      421 ttggttaatt aaagaaatcc cagtttatta agtatatctt tttcaagaat ctcaaggatt
      481 tctaagacat ctcgaccttt tgtaattggt ctgataatcc aatattctgc atttttctgt
      541 tttaagtcat catgttctcc atagttttct aagtcatcaa atgtgcaacc ccctacaaaa
      601 taaactttta cgttattttt aaaataatcc agagctttat ttttttcctg tttaaaagca
      661 ttttctaatc ttttgttata ttcccatttt tttaagtgag gattatatcc ataatctcct
      721 ggattgtgaa atattattct aaaataataa tctttattat gttctttcga cttataagat
      781 gtagtgtatg aacccaatat atcaaaatct ttatttaaaa tgtcatttaa gtcatattta
      841 gtggctattg atgacctaat ctctattgta attatctcat catttgaaag atgaatttct
      901 atgtcattgt gggattcata gttaaaattt tcattgctta catttgcacc tttgatttca
      961 atgtaatctt ttattaacat taatttttca gtaattaatt gttttacaac tttttctgca
     1021 ataagtccgc aaaatgatga caataatttt ctttcttctg ttcttatatc tccacttgga
     1081 ttcttttcac aaacatcttc tgctaatttt ttagcttcat catggatatt atttaattca
     1141 ttatcatcta attctacttt tattactaca aaaatatttt tttgtgatat aggggttatt
     1201 ttgcttccat tatatttatt tataggatgt ctatagtatt tttcaaatat aaatttcata
     1261 caatcacctt aatttttatt ccgtatctta cgcaccaatt catttgtatt tatggtattt
     1321 agtaatttaa taatattttg gcagtatttt aagcagtcta tggatttttc gtcatacttt
     1381 tttatgatgc cattaatttc attgcagatt tcgtttaatt cctcttttgg tattaagtct
     1441 tggaagtaaa tcccataaac taatgaatct attatatttt ctaaaaatat tctgtcattt
     1501 tcatttaatt tatcgtttaa ttcgaacctc aatttactta actgtgttaa agcgtttatt
     1561 atgtttttat ttttggggat tactataggt aactctctta attcttctaa ggtagtctgc
     1621 ctaaaatcat cttttaatgc tattgccgac tttccaatgt atatataaga tattaactca
     1681 ctatttagta ttcctaataa atagaagtaa ttaataggag tatctggctt taaaacaaac
     1741 acatacaaat ccttttttac aactccttca atatttccat aagatgccat aattctatct
     1801 tgtctattaa cgattctccg tataaagatt ttctcgggag acataaatag attaataagc
     1861 ttttcgttgt ttttatgttt tgagaaatca acataatttt ttaattttaa tttagtttca
     1921 tacctataca cattaccttc taaatatggc aaataatatt cgttttcttt tttatctgaa
     1981 aatttatatt ttgaagctaa aattcctatt gtagattctg ttaaatcttc caagtaagtt
     2041 agtgattctc tacaattttg tttaatttta tctaatatta tgtagatttc gggacttttt
     2101 gggaatattc gacactttgg gtcatttaat atttttgaat attctatgaa aaggtcattt
     2161 ttaaactcaa atgagatttt tttagttttt ttagggaatg catatatcaa aaccaaatct
     2221 tctgattttg gaggtttttt atgcagtatt attatacaat tatcaacata cgctcctgaa
     2281 aatacatcaa aaggtagata gattaatttt ttcagacaca tttttgtaaa taactctttt
     2341 ctaagatttg aatatctcac acccgttcca aaacttgatg ggattataaa tcctaaatac
     2401 ccctcatttt tcaataattt actactatgc actataaatg ttacaaaaat gtcaaattca
     2461 ggagtatctc tacgtttcat aatttctttt tcagtaggag atagcaaatt cccataaggt
     2521 ggatttccaa taattacatc aaaaccttcc tctttaataa tccatccgaa gtcaatcttc
     2581 caatggaagg gttttaattt ttcaaattcc tcaacacgtg gtctattctt tttacttttt
     2641 ttaccattat tctttttgtt atttccattt tggtaaatct cagcgaaata tgctggagtt
     2701 acactctcat atattgaatc tctaatttca tctaataatt cttttaacag attggcttta
     2761 agtccgtggc ttgttctata tacttcataa aggagatgat acgcttccac ataattgtct
     2821 aatacatatc catctctttt ttcaagcaat tctttagctt ttttcagttt ttttctctct
     2881 tcagaattgt gagcgttgat aattaaacct tcaagaacac acattatacg cacattatcg
     2941 cataggtagg agatggaaag ctgttttaaa ttttcatcaa tccatccaac taaactgtta
     3001 ccacatctta cattatactc aatatttggc agtaaaactt ctcctctttt taaagcctca
     3061 acgtctaaat tctcaataag agcaagccac aacctaagtt ttgctatttc aacagcaata
     3121 tcatcaatat caacaccata aagattgttt agtataatac ctaacttttc tttgtaaatg
     3181 tccatctctt ctctaagtaa ataataaatc cttttcttaa tttggagcaa ttcctttaat
     3241 gcagatatta agaaatgacc acttccaact gcggggtcta aaattcttat tttatccaat
     3301 tcatcaagaa aagctcttaa aatatgttta ttttcagcta ttttactatc ttcattaaga
     3361 atttcatcta atgttgagaa attaatgtca tttattttcc aatttttaat aatctcttta
     3421 aacctctcta caacaatcgg ctctattgta tttttggcaa tatagcttgt aatctcatct
     3481 ggagtataat aagcacccag tcctttctgc cctttttctg ccaaaatatt aattaacttt
     3541 tcataaacat acccaagaat atctggattt aattcaactt cttctgaacc ttcagatgta
     3601 gatagagtga atttatacct ttctaaaaaa ttaataacct ctccaataat ttcattatct
     3661 tttatagtaa atgatagttc gttaggaaca ttattactcc tgaataatcc accatttaag
     3721 taagggatgt ctttatagta aggattagtt ctaatatttt cttttctttc atcttctgga
     3781 gtattaagca cttcatagaa taatggttta agataagcat cataataatt tattaaaacg
     3841 ttagattttt tgtaatcttc ataagttctt ctaagcaaat ctcttgggac tattcccttg
     3901 tcctcaagga attttataaa tattaacctg ttcattaaca atactgcaaa ttttttcttg
     3961 tccaattctg atgtattggg tggagcttca atacaattgt ataagcattt tttagtgcct
     4021 ttatcttttt ctgaactact tttatctttt ttcttaacat ccttaacatc ttcaaatcca
     4081 aaaacaagtt ttacgaactc tttatagaat tcattagtaa tttcttcttt tttatgttta
     4141 atattctttg tagcaacttc aatatattct tcaatatact cctttgaaaa acaataataa
     4201 aactcagaaa atacctgttt taattcattt tctaaatctt tatctttttt attttcaaga
     4261 acatactcaa aaatagattt aagattcaat tctttgagag ttcttatttc tttaattgta
     4321 tcatcatagt gtaataacac ccattctaaa ccattagtgg ctataccagt atctacgcca
     4381 taagatttga taattaacca ctccttaacc tggtgaattc cagaatcttt tttatttaaa
     4441 tcactaccta aaggttcggc ttcgataaga atttctttgt taaatactga tactctataa
     4501 tcaggaattt ttctatctcc taatggtgat tttttagata tttctgatgt gaattcataa
     4561 cccaagaatt ctaaaattgg ttctataacc ttctgcctcg taaatggttc tggaagttgc
     4621 cctccaaaat catcagattt aaaattgtat ctaccctttt tcaataactc tttaaatttg
     4681 ccttctaatt ctggaatttg cttaatagac aaaataatat tcccaacaag cttaataaaa
     4741 tccttccact tgttataaac ttcttttgga atttctatat cagaacacaa ttttgtttga
     4801 gccataacta ccacctaaca tctaaaaaat ttaaattatt gattaattta aagtttcttt
     4861 aaaatttgct catattcgtc ctcttttaca tattttccac aaactggaat aaatctcttt
     4921 ggcttaacaa cttttggata ctttctaata ttttttaaga tgataactat ccatggtttt
     4981 ttctttttct taccatatcc ccacttttta tttgaatctt caatatattt tttaaattcc
     5041 tcttctgtta aaaataaatt atttttatat ttctcaagta tcttcatagg attttcaaaa
     5101 aattctactt cctcaatctc tgcctctcca taaaatccct gctcttccct tgaagcataa
     5161 aatattatct tcattccctt ttcaagtttt ggttaatgtt gctggtttga caaaaacatt
     5221 tttatgctca tccaaaatcc taccaattaa tgacttggga attggaaatg tagctcctac
     5281 aattttatca tccataacct cacctctatt atgtagaata ttttaatata gtgtttaaaa
     5341 tttattcttc aacctcacta ttttaaccct acctttctta acaatctcaa ctcttccctc
     5401 ttttttaagt tcatttaatg cagtataaaa ctttctcgta tcaacttcaa gtatttcaat
     5461 taatttccgt aatgcaataa tctttttcag attgtaagag ttccaacaat ctatttttaa
     5521 catcatctac tgtattagaa gattctttca aattatttcc atgtgaaatg ttaattatta
     5581 aaccattaac caaagtagat aatgtattta gttgattaac aatgtcattc aattctttct
     5641 tgctaacata atcattattg ttagagttaa taacattatt aaactctaat tgaattcttt
     5701 caatttcttt cttaatgaaa tttagttcgt tttcaaaatt atctaatttt ttattcaatt
     5761 tttcaaaatt ttcaaagatt tcttttcttt caccctctaa ctcttcaatt ttttcaatat
     5821 agttatcaat gcctaacagc ttaataatag cctttttaag cataataaca gctccaagca
     5881 gtgattaggt ttcattacct ttcattactc atcattatta taaatatagt aaataaaatt
     5941 taccttattt ttaatgtgtc cctcaattaa tttattatac aaaatgactg tccatattga
     6001 taaaatcggc aatatacgct ctataagtgg tatgcacttt gaaaattctt aacttatcct
     6061 gaacttttag gcaaccaata ataaataata tgcaatctcc tttttaattg attaattaat
     6121 caattaagca attaattgag tatcaattga ttaattgcaa aactttttat acttcaattg
     6181 agaaaagaaa atggttgaaa atagttaaaa acgaaaagct tatattttct tagaaatata
     6241 caactaaaaa aggttatcta ctctcaattg gttattacac aaaaagccta cccaatttac
     6301 aaacttggaa ttaactcacc tgtttatata aatgttacta aaaattagaa aagtagaaag
     6361 ataatgccct tatggtgttg tcatggaaag taaagaatat cgcaaattag agtataacta
     6421 taaagctttt ttaatttttt ctaaagttgc catgctaaca tttctaaccg tcggtattgg
     6481 tgctatattt acgccacaaa catatccaat aatgccaacc attggtttta tagttgttgc
     6541 tggaatcgta tccttaatag gtatgactat cggagcatta attattcacc aacaatatga
     6601 gacgttacca gctaacgaaa agttagaatt taaacaaaaa ctcctaccag aagcatacta
     6661 catttgtata gaattgtttg gttacggttc attagtatta ttatacaaca catttacatc
     6721 aaacaatcct acattatgcg ttatgtctct attaatggca ggattgttta tattggtagt
     6781 cttagtaatc tggtattttg gctacaaaag ttattaagta tcttattcct tagatgcatc
     6841 cttaactggc tttttaaata gccaataatt caaaactgca aaggcaataa ttaacaatcc
     6901 atacatcaac atggcagtaa agaatatcca caaattagca tcttccataa ccaccagccc
     6961 ctatttttct acttatgatt atggcaacta atgagatata aacctttact cctctaacgg
     7021 aattaaagca acaatatgcc ctttttggat tataatcctc tcaacttcct tatcatcaac
     7081 cttagcgtcc aaaaccataa tattaaacct atcctttgcc ttgacagttc cctcaacaat
     7141 cataccatta tctaagtaaa ttttacactt tttcttatga gcaaataata gcatataatc
     7201 cttataatcg tcatccttct tcttaggttg ctttttcatc ggttttcttt gtggtttatt
     7261 ctgcttattc aaattctcaa cctccttagc tattatatca taatgcttac ttttaatgtg
     7321 ctttttaatt gcctttacat ctgcattagt gtaattacag tatggacatt tatagaaaaa
     7381 tccctctttc tgtatttcca atttttcaat ataatcatct atgttcattt tttcaccaaa
     7441 tagttatttt tatccaactc ataatacttt ttataaatct ctatttgcgt ttttgcctct
     7501 ggtatgttct cttttagcca cttaatagag catactttac cattcctatc atagagatac
     7561 ctaacttcat aatctatatg tttgatgtat ttgttgccat acttggaagc ccaacggttc
     7621 aataacttta tagttttatc tcttccatag cctaacagct tacataatga agttaaataa
     7681 taacagcctc tcattttgcc atcttcccaa ttggaattga ttaactcatt aaggtagctc
     7741 tccaacttta ccttatttaa tacaacttcc ttatctccta tggttgtttt gatgtattcc
     7801 ctcttactat gctctacctt aggttttgcc ttcttattgg tgtttatttc caaatctatc
     7861 ttaatatcgt tattcacttt cttagttgct tgataatatc ttaaagcatc atccacaaag
     7921 tccgttaaat cccctcttat ctctccaaag ttttcatagt attttgttag cttccttatg
     7981 aagtatggct ttacattctg caaatatatc ggtttaaact tctccacttt gttaattgga
     8041 aacggtatgc ttatcggtgt ctttccctca atgtctgcat agtataagct aaatggtgct
     8101 gttacagtca tgttttcctt atagattgat aagtcaatac ccgtatctcc ttccttgcca
     8161 acaaaatcta acaacttcct tagcttaaag tttagaaagt ttgttaatat ggtgcttcct
     8221 tcaacatagc ccttatttag tatctcatta ggcaaatatc tggcattaat ccaaatatga
     8281 aagcccttac tcccactaaa ctttatgtgg atgtccttaa ctccataatc tttaaaaatc
     8341 tctcttactt ccttagctat ctccttagat ttcttaaagt tgcctttaaa gtcaatatct
     8401 ataacccaat cccaataatt gtagtcgata gctggatact ccaactcata tcttggactc
     8461 tcaaagtagt atggagagca gtaaatactc ctaaggttct ctataatcca atccttaaag
     8521 ttgcctctat aatcccataa atcaatatgc cttaaatatg gcttctcccc ctttgggatg
     8581 ttgttatagt tccaatactt tggatgtctc caattgattt ttctatctct atccaaatcc
     8641 aacctatggc aacttaataa cctatctaaa caaaaataat ataaatatct ggaagttagt
     8701 ttatagtagg taagcctatc catagctacc accattatag tggtctccat tggtcggatt
     8761 ctggattatc cacatctcca tttttccaca gctcttttaa aatcccccgt gctgtatctt
     8821 ccgatatgtt gaagttttca gcaatttcaa ccgtagtgta gatttttgga ttttgtagca
     8881 tgtagtttaa aatctctctt tttagttggg ataacttcct actttcctct ataagtttgt
     8941 taatctcttc taactcttca tccttttgtt gtgtttcttt tatctcttct ccaaccaatt
     9001 taaatatctc cttaacctta tctggtgctt taattcttaa caaaacccct aagattgtct
     9061 taaaccatat ttttaatgca tccctaacat cctctaaatc cacatactcc ttaaacttaa
     9121 gtttagcata agctttagcc atatactcaa tttgattaaa taatctatcg gaatatcctt
     9181 taaatagtcc gtaatctctc aataaatccc ttaacttctc ctctacctcc caaagtgtct
     9241 ttaatgcatc ttccttaaac tcaatatcct tatttttaat gtagctaatg aataaagcac
     9301 actcgtaagc ttccaaattc ttttgtttta tgaagttatt gtcttctctc aatctcttaa
     9361 ctttgtaggt gtgtagttta atctccttcc aatcctcgtt ggtgtatggc tttaatagat
     9421 agattaatgg aattctatct gtcattcccc tcaaattctt caaagtaaaa tccaatattt
     9481 ttgacaataa ccattctgat gcatttaact gggggttagc tcccaatata ttattaacta
     9541 tctttttagc cctatcttct gcctcatttc tatcatagtc atgttgtttt agtaactttt
     9601 tagcgaagta atttatcata gcttctttaa actcttcaaa tccctttaag tggtaaattt
     9661 cccaaagctc cattaagtca atatccttaa tgttccctac tccaatccat gggcttaccc
     9721 caatcattgg gatgttataa ccctctcttt ctctcttcca aatacctgaa gttttaccac
     9781 tttttaataa gtctaagtcg ttgcctactc ttaaaataaa gtccatcatc tcttcaataa
     9841 atatcggtct attgtggttc attgggatta ttcctttttt atagaatttt atgttatctc
     9901 tggagataac taaacctatt aagttctcta tgttaggcat atctactctt atcatgtcct
     9961 cagtagtgtt gtggagtttt gccaatggtt ctattgttaa actcttccct tgtccatagc
    10021 ttccaatgaa caaacaatca atagtttcag gctttaagtg tccatcccta tttttatccc
    10081 aatatatatg ggatgatgcc agtatctcca atgttattaa agtgtctatc gttggatttt
    10141 tcccttcttt gtccaatatt gccttcactt cgtaaaatac cctatcttta atataatcta
    10201 aggcattact ataaccagca ttcttaacct tcctaacaaa ggcatcataa ttgaaattta
    10261 tggtcttttg tggattgata cttaagccct ctatgtaata ctctccttta tggtttgttt
    10321 tcaaaattcc tacaatttca acatccctta ggttgttaat ctctggtgtg tatggaagat
    10381 aaaccctata aacttcatcc gtttctttta attggattat ggctatcgtt aaatcccttt
    10441 ccaactttat tggttctcca tcttcatctt tgaataggga ttctgaatat tttatgtctc
    10501 tgccacactc tggacactta attttataat cttggctgtt ttccactggc tcatacaacc
    10561 ttataacttc acaattacat cccttgttat tgccgttctt atccaaatca atacatacat
    10621 aacgtctcaa aattggtctg cttttcctat ggtgtattat tcccgcaata tctcccctaa
    10681 atacacacaa tttattccta aactctcccc aatccttagc ttttgtcatt atggtcctac
    10741 ttcttagtgt ctctaagcca attatgttaa tctctaaagg cttaaattgg aagtattttt
    10801 cataataaac tttataaatc atctctatgg cttcatacgg ttcatttaag agtaagctcc
    10861 taaagtaagc ccctacaatt ctctctttgc cctttaacct atcaacttcg ttaatgtcaa
    10921 attcaaagcc ctctggtgtt aatctctctt ctatgaattt tttaagtgat tttttcaaat
    10981 cttccataaa ttcgctttta gcttctgcct cttggaatgc ttttttaggt aaatactcat
    11041 ctaagatgtc tttaatgtct tcatagaatt tgtaagttag ataaatgtat tttctatcgt
    11101 aatcctctgg atttttcctt atgtcaatcc attctaattg tttgtaaatc tttaggtgtt
    11161 gctttaatgt tccttctcca attttcaact gctctatggc tttattcata aattcgtcaa
    11221 atctcatacc ttcaaaggtt aggattgtga atattttagc agttttttta caatcatcgt
    11281 ttttataact cttttttaat gtgttggctc tctcgccgat tttgttgcat aggtcttcaa
    11341 tcatactatt atcttgtata ttatgcagta attggtgaag catagtgaag tcgttatttt
    11401 gttggtgaag tgcagtgaat tcttcaccac attggtgaag catagtgaag tcgttatttt
    11461 gttggtgaag tgcagtgaat tcttcaccaa caatttcacc aatttttatg tctctatttt
    11521 gttggtgaag catttcacca gctttcacca attttaatac gacttcctta gggtcgtgta
    11581 tctcccagaa gctccaacct aaaattgacg taattgcatc ctccaatcta tatagtttgt
    11641 cggttggcaa ttctgcccct aactcccata aaccatattt taataatagt tgcctctctt
    11701 tcagaggtag cttgtttaat gaaaatagcc atatatttcc taagatttca gtattgtttt
    11761 tgttatgctc gtctaattct ttgatagtat tagggtcata tctaatgttc agtaatttta
    11821 tggcaacctc taaaacatcc tctggatatt gattaatttc attaattgta tattccaata
    11881 cattgttgtt ctgtatgtta tttatactac catttacata tttatccatg cctaaccacc
    11941 tctgttgttg ttaggttttt cggagttttg agggtatgga gatacctttt ataggttctc
    12001 cctatctttt ccagtatatt taataaagct atttttgaag ttttaacttt ataaacatta
    12061 aatgatgttc ttttatgtag cattatcaac ttgaaagcat tattttcaaa ttcgtgatat
    12121 agaaatcttt caaaagttga tattgcaaat acttttatgg aacatataca attatccaca
    12181 tttattctat tgtatcctaa aatcagttta gttaaatatt ccaatttata taatttatgt
    12241 gttgaagcat cttgatattt aaccaatgaa ccacaactta aaaataacat ctcatcttcc
    12301 aaaggtagat tacacaatga aaatagccaa tgggataaac ttaattttat ataatacaac
    12361 ttactataat agttagttag taactttata gtgcctttca atacattgtc agaatagcat
    12421 ttaatccatt taaccaaata ttccaaatct atgataatca aaaaatatat ataattgttt
    12481 atgacacaca tataatcacc tcctttgcag tggttttcca agtattttcc caatttgggg
    12541 aaggaagggg gcttaacact atttttttta atttcaaagt atataaacct tacgaaatta
    12601 tcggaattat ctgttccata ttcaggtaat ggcataaaag cttactggat tatatttaac
    12661 tattaaaatt tattaatttt attgagaata atgcggaatt tttacgcaga ggaatttttt
    12721 attatccaaa ctatcgattt agatagttct gatagattta aactattgaa gttattttat
    12781 gtaatatttt ctaaaattta cggacatttt ccgagattgc taccacgata ttgtataatt
    12841 aaacaaacac cacttaggtg aaaaatatac cagtaaagaa tacattcatc tcggaaaata
    12901 tccgtaacgg aaaattttca atgcacaaac ttttaattat ctgtaaatat aaaaattgtc
    12961 aataattatt ttatatttac cagtgaaatt tgaaaacgtg aaataatatc ttacatgtca
    13021 ttatactcgg aattttgcaa gtccttatat ttgaaatatc ggttacacac actattgtaa
    13081 aatactcgta cttatcggaa attttccgtg cggacatttt tcgaaggaag acataatttt
    13141 aagccataac aacataaaag agaatggatt acaaatacta cttcggaaaa tatccgcacg
    13201 gaaaattttc gcagtcagta gtatatacat cttccataag ttttgtaggt atgttatatt
    13261 catgttcatc aacgtttttt tctttcatca tgagataatt tacaattgct aaaatcaata
    13321 ttaatattat aaatccgaga attatcgcct tccacctaat ttttccagat tctaatgttt
    13381 cacataatac gcctaaacca aatataaaac taaaagcacc agtaatcgaa taaataactg
    13441 attttggagg aatattttca agattctcta taaacaactg ctcagaacgt gatttcagaa
    13501 ctctatctat tatttctctg tagcacttat tatcgttttc tttggttttc gaatcattta
    13561 tattttcttc aatttttaag ttttgattat tatttataat ttgaatatca ttttccgttt
    13621 ttttaacgtt taacgagttt tctatatttt cgttaatttt aaacgtctta aatagctgta
    13681 aagcaacatc aattaatttt tttccagata atttcataag attattgtat tcatccaata
    13741 tttctaaagt atgagtttta tttttcttag aatataagtg ctttaggttt aaaattttat
    13801 tttgtatgat tattttgtat gttttttcat taattttcat tacatgtccg attttttcaa
    13861 atattgataa taacttttca aaacctttta ctccaacgtt aaaatttcca gttttagaag
    13921 ataacgaata tctcttattt ttactatcat aagttgccga tatttctaag taactaatat
    13981 ttacataaaa attacagata atttcgtcgg gcatattcga caccttttta aaattcaact
    14041 gtaaattgac ggtttggtag tattatatta ttgtgattac aaagaatata cctttcggaa
    14101 aatatccgca acggaaaatt tccgaagtta gtagtgagac attgaaccta tatgttttaa
    14161 gagttagaac atgcccaaaa catgcttgta tattatatat gtaatgagta aattatgatt
    14221 agtatatttt tatccaaaaa atagagttca aaattagcgt tgctaaatcc cataacttat
    14281 gtggctataa agtaataagg ttatgaaatt atgaaattcc taacttccat aaacttctgg
    14341 aaattcacaa ctttcacaaa gttgtaaatg ttataaactt cagtagtgtc caaaaattat
    14401 taacctaagt tagactttgg gctgaaagtc caacttctat taactttgag accatttaat
    14461 atgtgcatat ttttaaatat ggaatatacc ctattaatcc atacaaaaat attaggtgag
    14521 tgggggatgt tatctaaaat cgaacgactt atattggcaa accaatacaa aattttgaaa
    14581 attttggaaa atacttcaga atatgatgag ataattaaga ttttagagga agggtatgaa
    14641 atattttatg atgaaatttt aggacatatt tttgatgaac ttccagaatc tgaaggacaa
    14701 tttgtattag atattctctc tttttacgac attgtagttg aaccctacaa acaaaagaac
    14761 cctaatgacc atgaaataat aaatcatcca tattcgtatt ttaaaggttt tgatggcaat
    14821 agcgaaacaa aatatatggc gtttgtaaga tttcttatag aagaccagaa aaaattttca
    14881 ttcgtagcaa agtatgcaaa gaaaactgat aattttaata gtcatttccc aatgttggat
    14941 aaatatagaa aaatggtaga gttatgggaa tcgaaataca ataaaaagta tgacttaaaa
    15001 agggaggaaa ttcttgacat cctaaatgca taattttatt tatctaaata tatttttaga
    15061 tttttatttt attataaaat tcaaaaaata tcttatcgta ttatagaaag atttgtaata
    15121 aactcattat aatagtgaaa tcttacttcg aaaatttcta accttggctg aactttgttg
    15181 attaagttca ggataaacaa aaaataaaaa gaacaatgat tttaaactca ctatcagtgt
    15241 agagattggc attaactatt tatttgtatt tatctatcat actgagagtt tttttatttt
    15301 cttttattgc tttattgatt tttctttgaa tgattctagt actattttct cataaggaaa
    15361 aatgtttggt ttgtcatctt aaatttaagt gatttgataa attataatta tcccaactta
    15421 aactgtaaat gaactacaat atcctttcct ttttgtttaa gttctatatc ttttattttt
    15481 gaacaatttc cacagaattc ttttcttaat atgtttttta tgtatcggca taaagattct
    15541 ttgattattg catcgtttat atcataccaa attgcataat ttttgagttc gaattcaaaa
    15601 tttggctttt tactcttcat tacctcatat atttctttaa taatattgtc ccagttaggt
    15661 ttaatatatt cttcatttaa taagttttta tcgatatatt tttcaatatt ttctttctgt
    15721 gagtcaaaac catttttctt tcgtattatt ttatagattt tataccctct tcctaaaatc
    15781 ctatggttag tggattgtat ttttatccat gtgttaattt cacgaatggg tagtcgttgg
    15841 tctattacat agatttttcc atttatctca atagctgcag caacatgcat aggatgagtt
    15901 actaaatata agttatagtt gggaaacaaa ttcgaaagta aagcaatagt tagtttagca
    15961 taatctctac atactgcttt tttgtatttt agaattttgg acactttaat atcataacat
    16021 aaagtatcat gcagcatagc gattgctgat acaaaatttc cattgcattg aaacaaatat
    16081 tttactatca atgtaagtat taacacccaa agtcctgaaa ttatactaat aattataaga
    16141 ttttcactga aaatatacaa tgtgaagata cttactaaca acaacatgct aatgttgttt
    16201 aagtattgtg aatattttga tggcaatgat attaatacta agagagccac tactgcagat
    16261 attacccata gtatcaatac cataatatca ttgattataa tctcaaaacc tattatcaat
    16321 aacaatacca taaataacaa taccacacca tataacatag ccgcaataac ataataaatt
    16381 aaagaatctg ccgctctttc catccaatat ctaatattag tttcttgcca ttccaaaata
    16441 ttatttaaag tttcaacaat tgaattttcc cataactgtt cagacagttt ttttatttcg
    16501 ttactataaa tttcttttag agaaggaata cttaaaaagt gtgacaactt
//
