LOCUS       NC_006675              13223 bp    DNA     circular BCT 15-FEB-2005
DEFINITION  Gluconobacter oxydans 621H plasmid pGOX4, complete sequence.
ACCESSION   NC_006675
VERSION     NC_006675.1  GI:58038467
KEYWORDS    .
SOURCE      Gluconobacter oxydans 621H
  ORGANISM  Gluconobacter oxydans 621H
            Bacteria; Proteobacteria; Alphaproteobacteria; Rhodospirillales;
            Acetobacteraceae; Gluconobacter.
REFERENCE   1  (bases 1 to 13223)
  AUTHORS   Prust,C., Hoffmeister,M., Liesegang,H., Wiezer,A., Fricke,W.F.,
            Ehrenreich,A., Gottschalk,G. and Deppenmeier,U.
  TITLE     Complete genome sequence of the acetic acid bacterium Gluconobacter
            oxydans
  JOURNAL   Nat. Biotechnol. 23 (2), 195-200 (2005)
   PUBMED   15665824
REFERENCE   2  (bases 1 to 13223)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2005) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (bases 1 to 13223)
  AUTHORS   Prust,C., Hoffmeister,M., Liesegang,H., Wiezer,A., Fricke,W.F.,
            Gottschalk,G. and Deppenmeier,U.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2004) Goettingen Genomics Laboratory,
            Georg-August-University Goettingen, Grisebachstr. 8, Goettingen
            D-37077, Germany
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CP000007.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..13223
                     /organism="Gluconobacter oxydans 621H"
                     /mol_type="genomic DNA"
                     /strain="621H"
                     /db_xref="taxon:290633"
                     /plasmid="pGOX4"
     gene            128..1102
                     /locus_tag="GOX2714"
                     /db_xref="GeneID:3248813"
     CDS             128..1102
                     /locus_tag="GOX2714"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase (class I)"
                     /protein_id="YP_190434.1"
                     /db_xref="GI:58038468"
                     /db_xref="GeneID:3248813"
                     /translation="MEGSIMGQIRHGSATTTHAVRAAIQRSQASLAALSEEFGINPKT
                     VAKWRKRQSVEDQKTGPKEPRSTVLSETDEAMIVAFRRHTLLPLDDCLYALQASIPHL
                     TRSALHRCLQRHGISRLPDIEGDKAKRQRFKRYPIGFFHLDIAEVQTAEGKLYLFVAI
                     DRTSKFAVTQLVEKADRKTAWEFLEHLLSIIPYRIHTILTDNGIQFADQPRNRNTAWS
                     RPMRFDMICEAHGIEHRLTKPNHPWTNGQVERMNRTIKEATVKRFHYDSHEQLRTHLN
                     DFMAAYNFGRRLKTLSGLTPYEYVCKIWTSEPERFIINPIHQTPGPNT"
     gene            1784..2269
                     /locus_tag="GOX2715"
                     /db_xref="GeneID:3248814"
     CDS             1784..2269
                     /locus_tag="GOX2715"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_190435.1"
                     /db_xref="GI:58038469"
                     /db_xref="GeneID:3248814"
                     /translation="MTSFACQIWTLSQSKQITAKTHLVLQALASFQGHRGLFPSHESI
                     AARSGASVRTVIRALETAYQLGIVERTRQRVRRSGRLVNGPNRYRLILTDLEKARVAA
                     AHAALRLKEALARRKQRILSNCHFGSGSHSQSDIFSYKPRSKNEWLDLIASWTGKPAP
                     T"
     gene            2694..3395
                     /locus_tag="GOX2716"
                     /db_xref="GeneID:3248815"
     CDS             2694..3395
                     /locus_tag="GOX2716"
                     /note="plasmid partitioning protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA-like protein"
                     /protein_id="YP_190436.1"
                     /db_xref="GI:58038470"
                     /db_xref="GeneID:3248815"
                     /translation="MHNGTKASVHMRTLAIAMQKGGVGKSWLTRSLAVAASQDNLNVV
                     VIDMDSQQSTVAWSERREADAPFVQFSTERELPALLKRAEDAGCDVVFIDTPPARSTE
                     TPAAVDAADMVLIPCTPDIEAYEQIARTERLARLAGKPALAVLTMTQPSGKSEQDIGQ
                     EIFANLKLAMALPSIARLKAHRDAAREGKTATETEPGGRAAQEIAALWMCIKEQANIG
                     TNAVVHKGKRAKVQK"
     gene            3392..3667
                     /locus_tag="GOX2717"
                     /db_xref="GeneID:3248824"
     CDS             3392..3667
                     /locus_tag="GOX2717"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_190437.1"
                     /db_xref="GI:58038471"
                     /db_xref="GeneID:3248824"
                     /translation="MSKKPTAGSFLDKMKRHDQTPQGEEPTPSAPKPVSKTRIGLKHI
                     GGYLDADTVEKVAILRARLRLDNSQLIKKAIEELFERENAARKFGDR"
     gene            complement(4095..5174)
                     /locus_tag="GOX2718"
                     /db_xref="GeneID:3248825"
     CDS             complement(4095..5174)
                     /locus_tag="GOX2718"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase (class II)"
                     /protein_id="YP_190438.1"
                     /db_xref="GI:58038472"
                     /db_xref="GeneID:3248825"
                     /translation="MKQAGFFDVEERLARLSGLGDQLEAFSRTVDFEVFRPELDKALA
                     YSDGSKGGRPPFDPVLMFKVLVIQTLNNLSDERTEYLINDRLSFMRFLGLGLSDRVPD
                     ARTVWLFRERLTQAGAIGGLFNRFDATLRNAGYLPMSGQILDATLVAAPKQRNTNAEK
                     ADLREGRIPQDWQDKPSKLSHKDRHARWTLKFTKAKRQEDGSIPATDLAIPFFGYKSH
                     ISIDRKFRLIRKWKTTDAAASDGARLREGLLDKSNTASTVWADTAYRSKANEDFMEKQ
                     GFVSKVHRKKPHLKPMPRHIQRSNAGKSVIRSRVEHVFADQKSQTGLFVRTVGITRAT
                     MRVGLANIVYNMRRFLLLERINAAA"
     gene            complement(5211..5609)
                     /locus_tag="GOX2719"
                     /db_xref="GeneID:3248826"
     CDS             complement(5211..5609)
                     /locus_tag="GOX2719"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="YP_190439.1"
                     /db_xref="GI:58038473"
                     /db_xref="GeneID:3248826"
                     /translation="MQHRYEGLDAHGDPLVALGAAVPFEMFRLKLKTALIKGGLRRSE
                     ADRKPWDEVLIFKVLVLQALYNLSDDQMEYQLRDRLSFMRFVGLGLEDAVPDAKTLWL
                     YREALARAGAVEALFDVEGSKNLLVLRPTL"
     gene            complement(5732..5899)
                     /locus_tag="GOX2720"
                     /db_xref="GeneID:3248827"
     CDS             complement(5732..5899)
                     /locus_tag="GOX2720"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_190440.1"
                     /db_xref="GI:58038474"
                     /db_xref="GeneID:3248827"
                     /translation="MEKLIKLLCAIADEHARRGNETASIKVINTIYEAWDLDIRTHSE
                     EVVENKFLKVS"
     gene            6241..7104
                     /locus_tag="GOX2721"
                     /db_xref="GeneID:3248828"
     CDS             6241..7104
                     /locus_tag="GOX2721"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase (class II)"
                     /protein_id="YP_190441.1"
                     /db_xref="GI:58038475"
                     /db_xref="GeneID:3248828"
                     /translation="MDDERTEYLINDRLSFMRFLGLGLSDRVPDAKTVWLFRERLTQA
                     GAVDGLFNRFDATLRNAGYLPMSGQILDATLVAAPKQRNTNAEKADLREGRIPQDWQD
                     KPSKLSHKDRHARWTLKFTKAKRQEDGTIPATDLAIPFFGYKSHVSIDRKFRLIRKWK
                     TTDAAASDGARLREGLLDKTNTASIVWADTAYRSKANEDFMEKQGFVSKVHRKKPHLK
                     PMPRHIQKSNAGKSVIRSRVEHVFADQKSQTGLFIRTVGITRATMRIGLANIVYNMRR
                     FLFLERINAHA"
     gene            7390..7698
                     /locus_tag="GOX2722"
                     /db_xref="GeneID:3248829"
     CDS             7390..7698
                     /locus_tag="GOX2722"
                     /codon_start=1
                     /transl_table=11
                     /product="truncated transposase"
                     /protein_id="YP_190442.1"
                     /db_xref="GI:58038476"
                     /db_xref="GeneID:3248829"
                     /translation="MAFPVPNPKAMLADRGYDSDGFRQDLLFRGILPVIPSRKGRNAP
                     QKTDWRRYRDRNRIERMFNRLKQMRRIATRYDKTALSFISFLNLAAARLWIESFVNAT
                     "
     gene            complement(7695..7928)
                     /locus_tag="GOX2723"
                     /db_xref="GeneID:3248830"
     CDS             complement(7695..7928)
                     /locus_tag="GOX2723"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_190443.1"
                     /db_xref="GI:58038477"
                     /db_xref="GeneID:3248830"
                     /translation="MSPVAPIVVRQISMVTFRKRRHGLTDTCDIICVDEDIPIRPDSL
                     SDFVRTILQIDVKLDDALLEMEKQKAFFSFLGA"
     gene            8188..8811
                     /locus_tag="GOX2724"
                     /db_xref="GeneID:3248817"
     CDS             8188..8811
                     /locus_tag="GOX2724"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_190444.1"
                     /db_xref="GI:58038478"
                     /db_xref="GeneID:3248817"
                     /translation="MKRPELMQGRLTLNLEEYSWPQTFCALYLLEETPVFAGISEEIL
                     NRYEADRDAVENFNSKGMEVTVSQVHRAVRLNRGLTRGAMAEGRRIAENICPDVRTSV
                     MDVTLMFLQTFIDSAEVSLRLLLLDREGLPEMVQDVLEEARSYQKRIAVFLPECDILP
                     LVARLLRKRCRMKKWVDIIEWIEACLSQEEGPLHFRDAIYSLTGEVF"
     gene            8943..9170
                     /locus_tag="GOX2725"
                     /db_xref="GeneID:3248818"
     CDS             8943..9170
                     /locus_tag="GOX2725"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_190445.1"
                     /db_xref="GI:58038479"
                     /db_xref="GeneID:3248818"
                     /translation="MIDLELKHMPGMTTGYMCKTDYDHELGEATGGVRVYASLADLKA
                     AQPCVETCGIVQVGIRFLKLVQNANWDRVQS"
     gene            complement(9290..9619)
                     /locus_tag="GOX2726"
                     /db_xref="GeneID:3248819"
     CDS             complement(9290..9619)
                     /locus_tag="GOX2726"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_190446.1"
                     /db_xref="GI:58038480"
                     /db_xref="GeneID:3248819"
                     /translation="MARMTLAEIKARPSTIDWTRVNATTDGDIDRQAKEDGTDVELPG
                     LAAPSPATVRRHLKLTQKDIAALAGVPVATWRNWEQGRVRLDPAVRTLLRVLWREPDA
                     VRRAMAA"
     gene            10097..10534
                     /locus_tag="GOX2727"
                     /db_xref="GeneID:3248820"
     CDS             10097..10534
                     /locus_tag="GOX2727"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_190447.1"
                     /db_xref="GI:58038481"
                     /db_xref="GeneID:3248820"
                     /translation="MQTFSCASRQALVPVVIRDGLMPDREGHGLLPDGLKGLLGHQTF
                     PDIPVPVIDPSGRFHAVAHGGRRCHRKPDQVRERDKLQRLLPGILLDLTAPVAEGRDS
                     LLEVLFVVLVDPDIHLDQAERFAALADGVHGLSAHEGTLQNLF"
     gene            10822..11475
                     /locus_tag="GOX2728"
                     /db_xref="GeneID:3248821"
     CDS             10822..11475
                     /locus_tag="GOX2728"
                     /codon_start=1
                     /transl_table=11
                     /product="truncated transposon gamma-delta resolvase"
                     /protein_id="YP_190448.1"
                     /db_xref="GI:58038482"
                     /db_xref="GeneID:3248821"
                     /translation="MAVFGYCRVSTSRQVGEGESLAVQERQIRGYAMQLGLEIDHIFV
                     EKGVSGSVSLADRPEGKALLERLEAGDTIITAKLDRMFRSAVDALGVLEDMKSRSVSL
                     HMIDLGGDVTGNGISKLVFTILSAVAEAERDRIRERISTVKADQKGRGRYLGGKVPFG
                     FAVGDGGALVQLPEQQAAIRHAKALRADDHSLRDIQAKLKRNGMPLSLAALHRILSA"
     gene            11608..12081
                     /locus_tag="GOX2729"
                     /db_xref="GeneID:3248822"
     CDS             11608..12081
                     /locus_tag="GOX2729"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="YP_190449.1"
                     /db_xref="GI:58038483"
                     /db_xref="GeneID:3248822"
                     /translation="MARGDLTDREWAIIGPLLPSERGRWARPSGDNRRFLNGMLYVLR
                     TGCPWRDMHERYGKWNSVYVRFRRWAEQGVWDALLQTLVDLGLSDDWQHMVDSTVVRA
                     HSQATGAKGGLIRRVLVAHAAALRAKSMPDVTIRDALSALSSPAGRSRTINPSML"
     gene            12081..12239
                     /locus_tag="GOX2730"
                     /db_xref="GeneID:3248823"
     CDS             12081..12239
                     /locus_tag="GOX2730"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_190450.1"
                     /db_xref="GI:58038484"
                     /db_xref="GeneID:3248823"
                     /translation="MALPAPNPRAMLADRGYDSDGFRQDLLIHGILPVIPSRKGRSVP
                     QSLNQKAV"
     gene            complement(12224..13054)
                     /locus_tag="GOX2731"
                     /db_xref="GeneID:3248816"
     CDS             complement(12224..13054)
                     /locus_tag="GOX2731"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase (class IV)"
                     /protein_id="YP_190451.1"
                     /db_xref="GI:58038485"
                     /db_xref="GeneID:3248816"
                     /translation="MAWTEITRAQYRRDDLEYASDLRDAEWALIAPLMPERKRLGRPR
                     RTDLRRVMEAILYIVTTGCQWRQLPRHFPAFTTVQGYFYRWIREGRWEAMNHILVILS
                     REQDGRDATPSVGIIDSQSVKTAENGGPRGYDAGKKIKGRKRHIATDTLGHVVAAVVH
                     PADVQDRDGAPLVAARIRSLFPWLRHLIGDGGYAGEKLRGALAELGRWTIEIVKRSDR
                     AEGFVVLPKRWIVERSFAWLGRCRRLTKDVEATISSSCAWLMIAHIRRILRKINQTAF
                     "
ORIGIN      
        1 cgacaagacc gccttatcct tcaacagttt cctcaatatc gccgcagcaa ggctctggat
       61 cagatctttt gtcaacgtga cctaggtgtt tagtccctgg gtttgatggt gtgatatttt
      121 cacgagagtg gaaggaagca ttatgggaca gatacgtcat gggagcgcca cgaccacgca
      181 cgccgtgcga gcagcaatac agcgatcgca ggcttcgctc gcggcgctga gcgaggagtt
      241 cgggatcaac ccgaagacag tggctaaatg gcggaagcga cagagtgtcg aagatcagaa
      301 gacaggtcct aaagagccgc gctcaacggt cctgtccgag acggacgaag cgatgatcgt
      361 ggcctttcgc cggcatacgt tgctgccgct ggatgactgc ctttatgccc tgcaggccag
      421 cattccccat ctgacacgct cggccctgca tcgctgcctt cagcgtcacg ggatttcacg
      481 actgccggac atagaggggg acaaagccaa acgccagcgc ttcaaacgct acccgatcgg
      541 gttctttcat ctcgacatag cggaagtcca gaccgctgaa ggcaagctgt acctcttcgt
      601 tgccattgac cggacaagca aattcgctgt cacacaactg gtcgagaaag ctgatcggaa
      661 gacggcctgg gaattcctcg aacatctcct gagcatcatc ccttaccgga tccacaccat
      721 cctgaccgac aatgggatcc agttcgctga ccaaccccgt aatcgcaata cggcctggtc
      781 gcgtcccatg cgcttcgaca tgatctgcga agcccacggg atcgaacatc gtctgacgaa
      841 acccaatcat ccctggacca atggtcaggt tgaacggatg aaccggacaa tcaaagaggc
      901 aaccgtcaaa cgcttccatt acgacagtca tgagcagttg aggacacacc tcaacgactt
      961 catggcagct tataatttcg ggcgaaggct caagacgctg agtggcctca cgccttacga
     1021 atacgtctgc aaaatatgga cttcagagcc agaaagattc atcatcaatc caatccatca
     1081 aaccccggga ccaaacacct agtaagggtt tttggtgccc ggcttcccgg tatagggatt
     1141 aatattccca cgcgtactcc agttatccga tttggtgtcg ttagggttgg tggcatgata
     1201 cccttgaact ggagttccgt tttgtctggt atatccagag gtatagtgtt ctccagtata
     1261 ggagcgcgga gtataggttc ttggcgtata agaatgtgga ttataagttc tcggtgtata
     1321 gctatacgaa tgatagccaa gactaacacg agcaatagca tcggtcgaaa taaacaaaga
     1381 tgcgactgct aaaagcggaa ttgtcatttt cattttgttt tatcctaaaa atctatcatt
     1441 acatttgtta cgattatttg cgctgaggat aattcaactc aaaggcgata aacgcaacag
     1501 cttttcaatg tttaacggtt caagcagtaa atttggacct gctggacggc cttaagagga
     1561 cgcccttgtc atctggctga cgaaattgca ttgtcttgaa aataagtgag gcggcggagc
     1621 taccaactcc aaccgcctcg aaactcgctg tttaccccgg cgagatatga tgaaaaggcg
     1681 attgaccccg ccaattcatc caatggctat attagggatg aagccgtatg gtttcaacag
     1741 cctttgaagc cgggaaagtg tctcgccgtc tgaaaggacg gatatgacct ctttcgcttg
     1801 ccagatttgg acgctctcac aatccaaaca gatcaccgca aaaacgcatc tagttctcca
     1861 agccctcgcc agttttcagg ggcatcgggg attgttcccc tcgcatgaaa gcatcgccgc
     1921 cagatcaggg gcgtccgtaa gaaccgttat ccgggcgcta gagaccgctt atcagcttgg
     1981 catagtcgag cggacccgcc agcgcgttag gcgttcaggg cggcttgtga acggcccaaa
     2041 tcgctatcgt ctgatcttaa ccgatctgga aaaggccaga gtggcggcgg ctcatgctgc
     2101 cttgcgattg aaagaagccc ttgcccgtag aaaacagcgg attctttcta actgccattt
     2161 tggcagcgga tctcattctc agagtgatat tttctcttac aagccacgat ccaaaaatga
     2221 atggctcgac ctgatagctt cttggacggg aaaacccgct ccaacctaac cagcccgacc
     2281 gacacagcca caaccgaacc ttccaatttg ctcaaggcga gggagccaga gacgagcagc
     2341 acggcctcac caacggtgca atggtgtatg aacaagccta tttcgtgccg gttccgtgac
     2401 agtaaaacag tgcccttcat acaccattgc accgttggtg cggacgggtc tgagaggccc
     2461 gcgaatgtct tacaatctgt gataggttcg atgatgtgga catgttttat tagagtttga
     2521 cgcaagattt ctcagggcgt gtgtcggaga tttgcagacc agtgtgccta tttttggcgt
     2581 gagaatctcc tctaaagatc gggcaggaca ggtgatgtga cgttgcacaa cacgccctgc
     2641 cttactcgcc aaggctcgac gggatataga tagttcaagg cacacatgca gttgtgcaca
     2701 atggaacaaa ggcaagcgtg catatgagaa ctcttgcaat agcaatgcag aagggcgggg
     2761 ttggtaagtc ctggcttaca aggtcgttgg ccgttgccgc ctcacaggac aacttgaatg
     2821 tcgtagtcat cgacatggac agccagcaat caacagttgc ctggtccgaa cgccgggaag
     2881 cggatgcgcc ttttgttcag ttctccacgg agcgggaatt acctgcactc ctgaagcgtg
     2941 ccgaagatgc agggtgcgac gttgtattta tcgacacgcc acctgcccga agcacggaga
     3001 cgccagccgc agttgatgcc gctgatatgg tccttattcc gtgcaccccg gacattgagg
     3061 cttacgaaca gatagcccgc accgagcgtc tagcacgtct agcagggaaa cccgctcttg
     3121 cagtcctgac catgacacag ccgtctggga agtctgaaca ggacatagga caagagattt
     3181 tcgctaatct gaaactggct atggcgttgc cgtcgattgc ccgattgaaa gcccatagag
     3241 acgccgcacg ggaaggtaaa acagctacag agacggaacc aggcggcagg gcagcgcagg
     3301 aaattgctgc actttggatg tgcataaaag aacaagcgaa cattggcaca aatgcagttg
     3361 tgcacaaagg taagcgtgca aaggtgcaaa aatgagcaaa aagccaacag ccggttcatt
     3421 cttggataag atgaaacgcc acgaccagac accacagggg gaggaaccga caccttcagc
     3481 acctaagccc gtaagcaaga cccgcatcgg cctaaaacac attggcgggt atctggacgc
     3541 tgataccgta gagaaggtgg cgatccttcg cgcacgcctt cgcctggata actcccagct
     3601 gatcaagaag gctattgagg aactgtttga gagagagaat gcggcccgca agtttgggga
     3661 tcggtaagtg ccaaggattg cgcatctgca ttaggctcag gacccattga tttttgtagg
     3721 gaattttgat tcaggctctg caaggagact gaagatggag agatcgaaga accgttgatt
     3781 gatgcgtctg gctcctgatt tcagagtttt ggcgtgctga ttgatggctc ctggggtggc
     3841 tttcgctctg cgttttgagc agatcgggaa cgatcatccg ctggactgct acgcgtgggc
     3901 gttaatcctc tcgaggaaga gaaagcggcg catattatag acgatattgg ccagtcagag
     3961 gtggagggtt cgaaaaacct ttgattgact tctcttgtgc ctgatttcag gtttttagcg
     4021 tgttgactgc tgcttccctg gtctaacttt tactctgggt tttgagcaga gcgatggttt
     4081 cctgctctgg attgctacgc ggcggcgtta atccgctcca ggaggagaaa gcggcgcata
     4141 ttatagacga tattggccag cccgaccctc atggtggccc gcgttatgcc tacggttcgg
     4201 acgaacagcc ccgtctgtga tttctgatcg gcaaagacat gctcgacacg cgagcggata
     4261 acggactttc ctgcgttgga tctctggata tggcgtggca taggcttgag atgcggcttt
     4321 ttcctgtgaa ccttcgagac aaagccctgc ttttccatga agtcctcatt ggcttttgag
     4381 cggtaggctg tgtctgccca gaccgttgaa gctgtattgc ttttatcaag caggccctcc
     4441 ctcaatcgcg cgccatcact ggcggcggca tctgtcgtct tccatttgcg gatcagccga
     4501 aatttccggt cgatggagat gtgcgattta tagccaaaga acgggatggc cagatctgtt
     4561 gcagggatac tcccgtcctc ctgtcgcttc gctttcgtga acttcagggt ccagcgcgca
     4621 tgcctgtcct tgtgggacag ctttgacggc ttgtcctgcc agtcctgagg gatccgtcct
     4681 tcacgcagat ccgccttctc cgcattggta ttgcgctgct tcggagccgc taccagcgtg
     4741 gcatccagga tctggcctga catcggcaga taaccagcgt tacgcagggt tgcgtcaaag
     4801 cgattgaaca gaccaccaat cgcaccagcc tgggtcagac gctctcgaaa cagccatacc
     4861 gttctggcat caggtacacg gtccgacagc cccagaccta aaaagcgcat gaaggagaga
     4921 cggtcgttga tcaggtattc cgtccgttca tcggacagat tgttgagtgt ctggatcacc
     4981 aggaccttga acatcagcac cggatcaaac ggtggacgcc cgcctttgct cccgtctgaa
     5041 taggccagtg ctttgtccag ttccgggcgg aacacctcaa aatccacagt ccgggaaaac
     5101 gcttcaagct ggtcgccaag accgcttaac cgagcaagcc gctcttcaac gtcaaaaaat
     5161 cccgcctgtt tcatagcgcc attcctccaa ccagaaccag aaaaatggaa tcacagcgta
     5221 ggcctcaata ccaagaggtt tttagaaccc tccacgtcga acagcgcctc gaccgcgccg
     5281 gcacgggcca atgcctcgcg ataaagccac agcgtcttgg catcgggcac cgcgtcctcc
     5341 aggcccagcc cgacaaagcg catgaacgaa agccggtcgc gcaactggta ctccatctgg
     5401 tcgtccgaca gattgtacag cgcctgcagc accagcacct tgaagatcag cacctcgtcc
     5461 catggcttgc gatccgcctc tgaacgccgc agcccgccct tgatcagcgc cgttttcagc
     5521 ttcaaccgga acatctcgaa aggaaccgcc gcgcccaacg ccaccagagg gtcgccatgc
     5581 gcgtccagcc cctcataacg gtgctgcaaa tcgaaaaatc caggctgacc catccctcaa
     5641 ccccaaagtt gacgcgctca tcgcgcgcta accctgaatc ccatttcagc cgatcaggaa
     5701 agccctattt ttcgaggtgc ccttaataat attaagatac tttcagaaat ttattttcta
     5761 ctacttcttc tgaatgagtt cttatatcta aatcccacgc ttcatatatt gtattaataa
     5821 ccttaatact tgcggtttca ttgccgcgac gagcatgttc gtcagcaata gcacaaagaa
     5881 gcttgatcag tttttccatt tttactttgt tttccagtat acgacgaaaa gcggtcgcaa
     5941 ctagactcta tagcatttat aaagtgatgt tttcttgatg aatgtcaagg aatcgttaaa
     6001 acatagaaca tgaatgcaaa tttaccgtaa attttcaatg cgttttgcta ctaacagcca
     6061 acggtgagat tttcgactca agactcatag ccaaaacatg ccgactgcgg cgagacagac
     6121 agatggccga gaaaaaaacg atcgtacacc tttcgtagcg ggttgtgact tggagggttc
     6181 gaaaaactct ctggttatga ggccctgtgt gtgattccat cgttcatctt acgatgaggg
     6241 atggatgatg aacggacgga atatctgatc aatgaccgcc tgtccttcat gcgttttctt
     6301 ggtctggggc tgtcagatcg cgtgcccgat gccaaaacgg tctggctgtt tcgcgagcgt
     6361 ctgacacagg cgggtgcggt cgatggtctg ttcaatcgct ttgatgcaac cctgcggaac
     6421 gctggttatc tgccgatgtc aggccagatc ctggatgcca cgctggtcgc ggctccgaag
     6481 cagcgcaata ccaatgcgga gaaggcggat ctgcgtgaag gacggatccc tcaggactgg
     6541 caggacaagc cgtcaaagct gtcccacaag gacaggcatg cgcggtggac gctgaagttc
     6601 acgaaagcaa agcggcagga ggatgggacg atccccgcaa cagatcttgc catcccattc
     6661 tttggctaca aatcccatgt ctccatcgac cgaaaatttc ggttgatccg gaaatggaaa
     6721 acaaccgatg ccgccgccag tgatggtgcg cgattgagag agggcttgct ggataaaacc
     6781 aatacggcct caatagtctg ggcagacaca gcctatcgct caaaagccaa cgaagacttc
     6841 atggagaagc agggctttgt ctcgaaggtc cacaggaaaa agccgcatct caagcctatg
     6901 cctcggcaca tccagaaatc caacgccgga aagtccgtta tccggtcacg tgtcgagcat
     6961 gtctttgctg atcagaagtc acagaccgga ctgttcatcc ggacagtggg tatcactcgt
     7021 gcaaccatga ggatcgggct ggccaatatc gtctataata tgcgccgctt tctcttcctc
     7081 gagaggatta acgcccacgc gtagcagtcc agcggatgat cgttcccgat ctgctcaaaa
     7141 cgcagagcga aagccacccc aggagccatc aatcagcacg ccaaaactct gaaatcagga
     7201 gccagacgca tcaatcaacg gttcttcgat ctctccaggt gcaaaagggg ggctcatacg
     7261 gagggttttg gtcgctcacg cggcggcttt acgagcaaaa tccacgcccg gtgcgacaat
     7321 caaggacgtc ctttcggctt tgcccttagc ggaggtcagg tctcggatta caaggccaca
     7381 gatgccctga tggcgtttcc ggttccaaac cccaaagcca tgctggctga tcggggctat
     7441 gacagcgacg gcttccgcca ggatctgctg ttccgtggga tactgccggt tattccatca
     7501 cgcaaaggcc gcaacgctcc acagaaaaca gactggcggc gttacagaga ccgcaatcgc
     7561 attgagcgga tgttcaacag gctcaagcag atgcgccgta ttgcaacccg atacgacaaa
     7621 accgccttat cattcataag cttcctcaat ctcgccgccg cgaggctttg gattgaatct
     7681 tttgtcaacg cgacctaggc gcccaagaag ctgaaaaatg ctttctgctt ctccatttcc
     7741 aaaagggcgt catcaagttt gacgtcaatc tgcagtatcg ttctcacgaa atcggaaaga
     7801 ctatcaggcc gtatcgggat gtcttcatca acgcagataa tgtcgcaggt atctgtcagg
     7861 ccatgacgtc ttttccggaa ggtgaccatg gatatctgcc gaacgactat cggggctacc
     7921 ggagacaaca gcgggccagc tgatccattc cttttccagt cactactttt tctgttctct
     7981 tcgactggag ggagcctttt tgccccaaga ctgagggcac agcaggagaa atgctgcgat
     8041 ggctgttgaa tgcagcgtta gactgaacag gagcggatcc gagttcaaaa tcgtcctgat
     8101 tgccacgtct gaaggtgatg tccgtcggat cgtgcggctt cagtacccgg gctataccat
     8161 ctgcgccgtc acgaccttgc ggtgtttatg aaaagaccag aattgatgca ggggagatta
     8221 accctaaacc tggaagaata ttcttggccc cagactttct gcgcccttta tcttcttgag
     8281 gaaacgcctg tctttgccgg aatctcggaa gaaatcctca accgctatga agcagacagg
     8341 gatgccgtgg aaaactttaa ttccaagggg atggaggtaa cagttagtca ggtccaccgg
     8401 gctgtgcggc taaaccgggg actgacccgg ggagcaatgg cggaaggacg ccggattgct
     8461 gagaatatct gcccagacgt caggacatcg gtcatggatg tgaccctgat gtttctgcag
     8521 acattcatag acagtgcgga agtttctctc cgtctgcttc tgctggaccg agagggtttg
     8581 cctgaaatgg ttcaggacgt cctagaggaa gcacggtcct atcagaagcg gatcgcggtt
     8641 tttctgcctg aatgcgacat tcttcccctt gtcgcacgcc tcctgcgaaa gcgttgccgg
     8701 atgaaaaagt gggtagatat catcgagtgg atagaggctt gcctgtctca ggaggagggc
     8761 cctttacact tccgcgatgc aatctacagc ctgacaggag aagtcttttg aatagcgggc
     8821 aaaaagtccg gcttcacgtg cagaagattc ggggcagaca tgtctggcct tgaacccgct
     8881 ttacccgtct ggagcttgat ctcacccagg cccatgaacg gacgaactgg atggaagagc
     8941 gtatgatcga tctcgaactc aagcacatgc ccgggatgac gaccggttat atgtgcaaga
     9001 ccgattatga ccatgaactt ggcgaagcaa cgggaggcgt acgcgtttat gcttctctgg
     9061 cagacttgaa agccgctcag ccctgtgtgg agacctgcgg aattgtgcag gtcggaatca
     9121 gatttttaaa actggttcag aacgcaaact gggatagagt tcaatcgtga gtaacagcag
     9181 cccgcttccg taagtagtca cttcctgaca caactctttt tatccctgca ggcctttcta
     9241 gtatccgata agccttacta taattttcct taagtaaact tcgatccagt tatgcggcca
     9301 tcgcccgacg tacggcgtct ggctcacgcc agagcacacg aagcagggtc cgcactgcgg
     9361 gatccagcct tacccggccc tgctcccagt tccgccaggt agcaaccggc acgcccgcca
     9421 gggccgcaat gtctttctgg gtcagcttca ggtgacgccg cacggttgcc ggtgacggag
     9481 cagccagccc cggaagctcc acatccgtgc catcttcctt ggcctggcga tcaatgtcgc
     9541 cgtccgtggt cgcgttcacc cgcgtccagt cgatcgtaga ggggcgggcc ttgatctctg
     9601 ccagtgtcat tcttgccatt tgatccactc cttccggtgc atttttcggg ctgagatgat
     9661 ccggaagcag tcgccccgga ccgtatagac gaccatgaac gggacgcctt caatcaagcc
     9721 tgcggccctg atgcgcggct cgccataatc tttccgatca tccggcttct gaagcagcgg
     9781 ccccgcaaag atgaccagta cattcgcaaa actaaatccg cgctcttcga gacaggcatc
     9841 gcttttcgcg tcatcccatt caaacgcgat ctgaggtccg gctatgcatc tctatatgcg
     9901 ctgctagcgc acacaagaca acgctttcat agctttctga aagagggtcc tggatccgac
     9961 agccgctcta ccagagagct ccaaccacct gcggctgacg ccagaaaagc cctctaaact
    10021 gtagcataag cgtagcatgg ccgtagcatc catgtagcat gggagaagct cgtttcaggg
    10081 tcgcgcgtat atacaaatgc aaactttcag ttgtgcatcc cgccaggcac tagtgccagt
    10141 cgtaatccgt gacggcctga tgccggaccg tgagggtcac ggcctcctgc cggatggcct
    10201 caagggtctc ctcggacacc agacgtttcc agacatcccc gtcccggtca tagacccatc
    10261 cggacgcttt catgctgttg cgcacggcgg ccggaggtgt caccggaaac cggaccaggt
    10321 acgtgaacgg gacaaactcc aaaggctcct ccctggcatc ctgctcgatc tgacggcccc
    10381 ggtcgcggaa gggcgcgaca gccttctgga agtcctcttt gtcgtcctcg tggatccaga
    10441 cattcatctg gaccaggccg agcgctttgc ggcgctggcg gacggcgtgc atggtctgtc
    10501 ggctcatgaa ggaacactcc aaaatctgtt ttgaagcttt tagcactagt gctcagtgag
    10561 acgcacacct gaaagggtgc atttgtatat ggagaagaga aaatcttgat atcgaagtga
    10621 tactcttgtg ataccgacct gataccgttg cgatactctt ctgagaccct ctaatatcga
    10681 cagatcccgc gcaacgaacg gtatcaagca gtcctttctg gtgtctgaga acgctccttc
    10741 ccgattgttt gttcgcttgt aatagcacac gaacgtattt atcagcgtcc ggacgcaagc
    10801 gaacaagcga acggatgggt catggctgtt tttggatatt gccgcgtttc aacgtccagg
    10861 caggtcggtg aaggcgagag cctcgctgtc caggaaaggc agatacgcgg gtatgcgatg
    10921 cagctggggc tggagataga tcatatcttc gttgagaagg gcgtttccgg ttctgtgtca
    10981 ctggcagacc gtccagaggg caaggcgctc ctggagaggc ttgaagccgg tgatacgatc
    11041 atcacggcca agctggaccg tatgtttcga tctgcggtgg atgccctcgg cgttctcgag
    11101 gacatgaaaa gccgttcggt gtccctgcac atgattgacc tgggcggcga tgtaaccgga
    11161 aacggcatca gcaagctggt gtttacgatc ctgtcagccg tggccgaggc agaacgcgac
    11221 cgcattcgtg agcgcatcag cactgtgaag gctgaccaga aaggccgggg ccgctacctg
    11281 ggcggaaagg tgccgtttgg ttttgctgtc ggggatggtg gcgctctggt gcaactcccg
    11341 gagcaacagg cagcgatacg ccatgcaaaa gcccttcgtg ctgacgatca cagcctccgg
    11401 gatattcagg ctaagctaaa gcggaacggg atgcccctgt ctctcgcagc cctgcatcgc
    11461 atcctgtccg cctgaggcct ttacccgaac ggccaccatt tccgacgtgg gagatacgct
    11521 aggccacgtt gacaaaagat ctatgcgatc agcctgagat ctgattcatt tccttcctgt
    11581 ggggtaaaga gcagagagag agcggacatg gcacgaggcg atctgacgga tcgggaatgg
    11641 gcgataattg gtccgcttct gccttctgag cgtggacgtt gggcgcgccc gtccggagat
    11701 aaccgccggt ttctcaacgg catgttgtat gtcctgcgca ccggttgtcc gtggcgggac
    11761 atgcatgagc gctacggaaa atggaactct gtctatgtca ggttccggcg ttgggctgaa
    11821 cagggtgtct gggatgccct gctgcaaacc ctggtggacc tgggtctgag tgatgactgg
    11881 cagcatatgg tcgacagtac cgtggtccgc gcccactccc aggcaacagg tgcaaaaggg
    11941 gggctcatac ggagggtttt ggtcgctcac gcggcggctt tacgagcaaa atccatgccc
    12001 gatgtgacaa tcagggacgc cctctcggct ttgtcctcac cggcgggcag gtctcggact
    12061 ataaatccgt caatgctctg atggcacttc cggctccgaa ccccagggcc atgctggctg
    12121 atcggggcta tgacagcgac ggcttccgcc aggacctgct gatccacggg atcctgccgg
    12181 ttattccctc acgaaaaggc cgtagcgttc ctcagagcct gaatcagaaa gcggtttgat
    12241 tgattttccg cagaattctg cggatatggg cgatcatcaa ccacgcgcag gatgacgaga
    12301 ttgttgcctc gacatccttc gtgaggcggc ggcagcgtcc gagccatgca aagctacgct
    12361 ccacgatcca gcgtttgggc aggacgacga agccttcggc ccgatcgctg cgcttgacga
    12421 tctcgatcgt ccatcggccg agttcagcca gcgcaccacg caacttctcg ccggcatacc
    12481 ctccgtcacc gatcagatgg cgaagccagg ggaacaatga gcgtatcctg gccgctacca
    12541 gcggcgcgcc gtcacgatcc tgaacgtcgg cgggatgcac gacagccgcc acgacatgac
    12601 ccagcgtgtc ggtcgcgata tgccgcttgc gtcccttgat cttcttgccc gcgtcataac
    12661 cgcgtgggcc gccgttttca gcggttttaa ccgactggct gtcgataatg cccaccgaag
    12721 gcgtggcgtc tcgtccatcc tgctcacgcg acaggatcac gagaatatgg ttcatggctt
    12781 cccatcgtcc ctcgcggatc cagcggtaga aatagccctg cacggtcgtg aaggcgggaa
    12841 agtgacgcgg caattgccgc cactggcagc ccgtggtgac gatatagagg atcgcctcca
    12901 tgacccggcg caaatccgta cgtcggggtc tccccagtcg tttcctctcg ggcatcagcg
    12961 gcgcaatcag cgcccactcc gcgtcgcgca ggtcgcttgc atactccagg tcgtcccggc
    13021 gatactgcgc tcgggtgatt tcagtccagg ccatcttgat ctcatcaggt tatcgcaaac
    13081 ccatgaatca taacctgctg aaatcactca actcatttta ggtcaggctc tcagaaaaca
    13141 gactggcggc gttacaggga ccgcaaccgc atcgagcgga tgttcaacca cctcaagcag
    13201 atgcgccgca ttgcgacccg cta
//
