LOCUS       NC_009897              15286 bp    DNA     circular BCT 28-NOV-2007
DEFINITION  Rickettsia massiliae MTU5 plasmid pRMA, complete sequence.
ACCESSION   NC_009897
VERSION     NC_009897.1  GI:157954006
KEYWORDS    .
SOURCE      Rickettsia massiliae MTU5
  ORGANISM  Rickettsia massiliae MTU5
            Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
            Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
REFERENCE   1  (bases 1 to 15286)
  AUTHORS   Blanc,G., Ogata,H., Robert,C., Audic,S., Claverie,J.M. and
            Raoult,D.
  TITLE     Lateral gene transfer between obligate intracellular bacteria:
            Evidence from the Rickettsia massiliae genome
  JOURNAL   Genome Res. 17 (11), 1657-1664 (2007)
   PUBMED   17916642
REFERENCE   2  (bases 1 to 15286)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2007) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (bases 1 to 15286)
  AUTHORS   Blanc,G., Ogata,H., Robert,C., Audic,S., Claverie,J.-M. and
            Raoult,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-APR-2007) Laboratoire Information Genomique et
            Structurale, PARC Scientifique de Luminy, Marseille 13009, France
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CP000684.
            Source DNA is available from Pierre-Edouard Fournier,
            Pierre-Edouard.Fournier@medecine.univ-mrs.fr.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..15286
                     /organism="Rickettsia massiliae MTU5"
                     /mol_type="genomic DNA"
                     /strain="MTU5"
                     /db_xref="taxon:416276"
                     /plasmid="pRMA"
     gene            106..2442
                     /locus_tag="RMA_p01"
                     /db_xref="GeneID:5664847"
     CDS             106..2442
                     /locus_tag="RMA_p01"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001497185.1"
                     /db_xref="GI:157954007"
                     /db_xref="GeneID:5664847"
                     /translation="MQSFYPLATPSDNVGIHQYYDTTKNQSYVPITGCVLSHILSSKE
                     LSTLEKMYYILADGLSCINFSKGRNRSISLPAKSWAERLSCSKSEVFVLQKSLEDKGH
                     FIITRDKNDQGQNKRNIITTTIPDKVFNDLKYEPDRFDLGDIDNTKTRHSKSDKLDSI
                     DNIFVSTIEGKRQHLEKTKMFIRVPYEFLKQLNSNCSISATAKTITLYLFTKIYKSSL
                     SSNNDKGNRDTDSKEKDNRITTETYIDASNSNKNDYKDVYDHAYDHDHSITNNLHSIV
                     TSYQELQKELKLHRNSISRALKDLEDNNLIKRDKLVIRNNDDYNSRADKSLWQISLLN
                     ISLINNNDQKKQKEQKQQIVIEYNNNKALEIAKEWKCTEYDPPCTDSGQLYNKDFVLK
                     NSIIKNIDYIDVNLKNLSCKKEFLGNELCSFPSECYNNSSFLNDSEAGCFVSKKEYYE
                     TASFKLPCANIHPEIVARTIKDISENKELRHFYPLSEKDVDMLNFKANRGFSTNFVNQ
                     LLLKLYIKYPEKKFKNKFTFLSYMEKVLASEKHQGPLVNHTTFRFSCNIGAEEQNMLE
                     HEQYLSHIENSFDTSKEMQVKKKIAGRFSTSIAYSILTQVEFKINANNSFITVLIPSN
                     LALSERQIEILSEQLEAVYGMNGYYVQEVEEMEDTSNERNRRDEEKVMLYPKITTSDI
                     VSNGTHAGILAKSGGLDTIEVDTAWHHIRQGLIEELGEAMYTAWFEEVVVKECNDTST
                     LKLTMPTRFMANWVRNNYSHVIQRLGSSAGVKRVEYGY"
     gene            2693..2971
                     /locus_tag="RMA_p02"
                     /db_xref="GeneID:5664849"
     CDS             2693..2971
                     /locus_tag="RMA_p02"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001497186.1"
                     /db_xref="GI:157954008"
                     /db_xref="GeneID:5664849"
                     /translation="MDLPMLTKLKELESENVRLKKMYAEERLRADKTINDCWSMDFIM
                     HNSLENGRRYRYIMLYQVRFYAVGYTLRRLDSHQLFLTHFAWHTGGWT"
     gene            complement(2994..4574)
                     /locus_tag="RMA_p03"
                     /db_xref="GeneID:5664852"
     CDS             complement(2994..4574)
                     /locus_tag="RMA_p03"
                     /codon_start=1
                     /transl_table=11
                     /product="Leucine-rich repeat protein"
                     /protein_id="YP_001497187.1"
                     /db_xref="GI:157954009"
                     /db_xref="GeneID:5664852"
                     /translation="MWTDQNSIKNSLSMLKKRVSYNTQIKERHLEKQRYTEKNLSSDG
                     ELSTNQLQEIKIANTSNKNPNLNDHHAYLKYYLKCINTYTNTTSSMQMKSDYELNYIN
                     KNLLIDAVIQNNQNTNNPPSKTFNKKLQYVQGYKKKDKLFCTEVNLHLQNNSDNTNCS
                     SDVLSSQKRRSQQKNCINIITIKFISDDNIMNIRIEELMTIFKDTQIIYLDLSNNNIG
                     DTEIKILTPMLKDAQITYLNLRQNYIGDIGVRELAKILNNMHITSLNLSSNAINDTGT
                     VELAAILKNTQITHLDLSSNNVGDTTIDDAVEKLAAILPDTQITHLNLGYNSIDAAGI
                     IALAKILKDTKITYLNLEFNNVDNTGAIALAKILKDTKITYLNLDCNAIGLYGIRILT
                     ATVKEMNIIIHLTGQQPYHETDYYDGHFSKLQRIEFPQLDPDLVREMANSKSDHTSGN
                     EENDSGCEVWDWDAESDDISDTDSNGTMTIRIGHSNEDVNIDTIKSRIYGINKTPDIE
                     VIHNAQILTEDIDCMGAL"
     gene            complement(4665..6200)
                     /gene="spoT22"
                     /locus_tag="RMA_p04"
                     /db_xref="GeneID:5664848"
     CDS             complement(4665..6200)
                     /gene="spoT22"
                     /locus_tag="RMA_p04"
                     /codon_start=1
                     /transl_table=11
                     /product="Guanosine polyphosphate
                     pyrophosphohydrolase/synthetase"
                     /protein_id="YP_001497188.1"
                     /db_xref="GI:157954010"
                     /db_xref="GeneID:5664848"
                     /translation="MTYQHIITILQRYDHHFDCTQFDKAIKFLLKYCHNNKYSLEISE
                     TLISIYPDTKSVITSLLFFTELKNHLTLTHIKYHFGEEIATIFFSLAELFRIQNTYCN
                     TIQETFQLFCSLKPNIAIRILLIRFAYLLHKIIFNCNISDIEYYLMSEEIKDIYVPLF
                     KEITVEKINNVLQNVCLEILQPKLYKFITDFLKVNYQNPDQLVIKVINSFHDILSRLD
                     VAYAISGRVKSTYSIAQKLVNKSNEIKNLCDIIGIRVIVTQDNECYKVLNTILNYYAH
                     VPKRNKDFIKCPKKNNYQSLHTVIIDKDLRKLEVQIRTRRMHSIAQSGSASHLQYKLN
                     LQNCNNLDVTHNILNKFIFNTLNQYSSIPTIVPKYLRINRLDGLISYIIGSIKPNDRT
                     LKQDVSIYHENTRYYVDTAKIVNVNQKTLILVSKGKPYIATDTGKTSQLQDVSIYHEN
                     TRYYVDTAKIVNINQKTLILVSKGKPYIATDTGKTSQLQDVSIYHENTRYYVDTAKIV
                     NIN"
     gene            7464..8015
                     /locus_tag="RMA_p05"
                     /db_xref="GeneID:5664844"
     CDS             7464..8015
                     /locus_tag="RMA_p05"
                     /codon_start=1
                     /transl_table=11
                     /product="Site-specific recombinase"
                     /protein_id="YP_001497189.1"
                     /db_xref="GI:157954011"
                     /db_xref="GeneID:5664844"
                     /translation="MATVGYARVSSSGQSLSVQLDKLKDCDKIFQEKKSGFGGTRSVL
                     KNALDYVREGDIFTVTKLDRLARSTAHLCKIAEILEQKSVALKVLDQNIDTKDATGRL
                     IFNVLGAIGQFETEIRAERQMDGILKAKERGVKFGKKKYLTHEQLSALKEKREQGVKI
                     KTLMQEFNLSKATIYRYLAQELI"
     gene            complement(8200..9243)
                     /locus_tag="RMA_p06"
                     /db_xref="GeneID:5664845"
     CDS             complement(8200..9243)
                     /locus_tag="RMA_p06"
                     /codon_start=1
                     /transl_table=11
                     /product="Transposase"
                     /protein_id="YP_001497190.1"
                     /db_xref="GI:157954012"
                     /db_xref="GeneID:5664845"
                     /translation="MTNEEHNQKQQQTELENSGVSERPRHDELFKKVMSEPIAAREFL
                     EHYLPVSFKNKINLNSVKIEKESFVTEDLKKRFSDVVYSVSLKNDNVKDSTTDSVDND
                     KAYVYVLIEHQSSSDYWIAFRLWQYMLLLCERYKDANKGNNKQERDKLPLICPIVVYA
                     NDKPYNAPRSFWELFEDSNTAKTLMLDEYLLVDLQKQSDDEIEKKKHLGMMEYMLKHI
                     KARDILNLWQSLLERFKSSIEIDKKNGYIYIKWLLWYSDAKVDADKQAELAKIIAKHL
                     NKADGEGLMRTIADKYIDEGIAQGMQIGKNEGKHERTMEVAKNMLSNNYSIPEVSRIT
                     GLSISEINNLLKA"
     gene            9242..9514
                     /locus_tag="RMA_p07"
                     /db_xref="GeneID:5664850"
     CDS             9242..9514
                     /locus_tag="RMA_p07"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001497191.1"
                     /db_xref="GI:157954013"
                     /db_xref="GeneID:5664850"
                     /translation="MLVNPYNLMVIVCSNSFSRRGSLTSAFTLAKVDATGFSSTKPGI
                     LFCIPCFIYLSEYEYFLALTIACSSSNSCFHHDAPYNTSHMLYLKF"
     gene            10001..10312
                     /locus_tag="RMA_p08"
                     /db_xref="GeneID:5664851"
     CDS             10001..10312
                     /locus_tag="RMA_p08"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat domain protein"
                     /protein_id="YP_001497192.1"
                     /db_xref="GI:157954014"
                     /db_xref="GeneID:5664851"
                     /translation="MRGLDKLERKIIKKLQRYKIDGVGKISATNHKQRIPRMHHENAP
                     ANCYVGMIPQKQGRYHESLATYRKAISLRPGASVFAFYICVISKVLVGITNVYTEYIR
                     N"
     gene            10321..10590
                     /locus_tag="RMA_p09"
                     /note="Transposase"
                     /pseudo
                     /db_xref="GeneID:5664842"
     gene            complement(10933..12009)
                     /locus_tag="RMA_p10"
                     /db_xref="GeneID:5664853"
     CDS             complement(10933..12009)
                     /locus_tag="RMA_p10"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001497193.1"
                     /db_xref="GI:157954015"
                     /db_xref="GeneID:5664853"
                     /translation="MIQESLGQNIKSLVPVNTPLLYEHQCLTDESVLIKNVHKVVLQG
                     HDISMRTPKTGKCGIFLIKYMSDKLKHMLQEVTPDVINNTTSSILDFFFTTVTENTSL
                     NYTNEVIDYNSTNSTDISNYDEQHSQDSTMLVSGLVLASAVSITYLLTCMYNKYCKKT
                     PVAQTETAADINISDPTLIEINNRKAKIYYSDSSSADGTEYAIVDIVSKRATYTKATY
                     DTSNPSSSHSDDHDRMELMSPSSSHSDDHDRMELMSPSSSHSDDHDRMELMSPSSSHS
                     DDHDRMELMSSTDSSTQESSHVNSHRLAQLHIEDSDSGIPICDNCAPIYDYPQLPPRL
                     ATVYIPIVQHYDDSSILGLSEFLC"
     gene            complement(11942..12316)
                     /locus_tag="RMA_p11"
                     /db_xref="GeneID:5664843"
     CDS             complement(11942..12316)
                     /locus_tag="RMA_p11"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001497194.1"
                     /db_xref="GI:157954016"
                     /db_xref="GeneID:5664843"
                     /translation="MNEIFPLLLNTFRTIWGNTNTCEDSNKTFDVVKLGNMLRNRKYY
                     LMDQQLISSKCFPTDNCSLDTKVACNIFELLSKSTNSLGLKAYVEHLNGTIFRIVSSF
                     NDTRIFGTEYKIFSPGKHSIIV"
     gene            13299..13784
                     /locus_tag="RMA_p12"
                     /db_xref="GeneID:5664846"
     CDS             13299..13784
                     /locus_tag="RMA_p12"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001497195.1"
                     /db_xref="GI:157954017"
                     /db_xref="GeneID:5664846"
                     /translation="MDISLRIQKFLSQKIKTYKIQQKDLVLGTSLSRSTISKLLNAIL
                     LNPNIITILKIATFFECDIDEVLGRAKFIKNTKKYQLYVSLTLNDINNHLLSFLKTKI
                     QQLNITEYILEKNCRVGSSTITHFINTNSDNRILSTKVIVKLADYFQISIDEMIGRTK
                     I"
     gene            complement(14197..14838)
                     /gene="parA2"
                     /locus_tag="RMA_p13"
                     /db_xref="GeneID:5664854"
     CDS             complement(14197..14838)
                     /gene="parA2"
                     /locus_tag="RMA_p13"
                     /codon_start=1
                     /transl_table=11
                     /product="Plasmid stability protein ParA"
                     /protein_id="YP_001497196.1"
                     /db_xref="GI:157954018"
                     /db_xref="GeneID:5664854"
                     /translation="MILSFLNQKGGVGKTTLSINVATCLSLKKQKVLLIDADPQNSSL
                     DWVAIRRKESLFTVVGLTKPIIHKEVSKLVKNYDHIIIDGPPRIYDVAKSAIVTSDLV
                     VMPVQPSPYDIWAANEVVSLIKEVSQPLEGRKNIKSAFLINRKISNTAIGRDVEQALD
                     HYGMDILQTHICQRVAYAETAAIGSTVMEEHNRDNLAVREITDLTNEILEKYN"
ORIGIN      
        1 ttgatacgat atgcaaaaat aaacacgggc agcattattt ttacacgtaa taaatatata
       61 ctatttctac gtagcggtca agggtttcag aaaaaggagc ataaaatgca atcattttac
      121 ccgcttgcta cgccaagtga taatgtaggt atacatcagt actatgatac caccaagaat
      181 caatcatacg tcccaataac tggatgcgta ttatctcata tattatcaag caaagagtta
      241 tctactcttg agaaaatgta ctacatctta gctgatgggc tttcttgtat taacttttct
      301 aagggacgta atagatctat atctctacct gctaaaagct gggcagaaag actatcttgc
      361 tctaaatctg aagtatttgt gcttcagaaa tccctggaag ataaaggaca tttcattatt
      421 actagagata agaacgatca aggtcagaat aaacgtaaca ttattaccac aacaataccc
      481 gacaaggtct ttaatgatct taaatatgaa cctgataggt ttgatctagg tgatatcgat
      541 aatacaaaaa cacgtcactc taagtcagat aagttagatt ctatagataa tatctttgtg
      601 tcaaccatag aaggaaaaag gcaacatctt gaaaaaacta agatgtttat aagagtacct
      661 tatgagttct taaagcaatt aaattctaat tgtagcattt ctgcaacagc aaagactata
      721 acactctatc tttttacaaa gatttataaa tcttcattat ctagtaataa tgataaaggt
      781 aacagagaca cagacagtaa ggagaaagac aacaggataa ctacagagac ttatattgat
      841 gccagtaaca gcaataagaa tgattataaa gatgtttatg atcatgctta tgaccatgat
      901 cactctataa ctaataatct gcactctatt gtcacttctt atcaagaatt acagaaagaa
      961 cttaaattac atagaaattc tatttctaga gcattaaagg atttagaaga taataatctt
     1021 attaagcgag ataagttagt tatcagaaac aatgatgatt ataatagcag ggctgataaa
     1081 tctttatggc aaatatctct tctgaatata tctctaataa ataacaatga tcagaaaaaa
     1141 cagaaagagc aaaagcaaca aatagtaatt gagtataata acaataaagc cttagaaatc
     1201 gctaaagaat ggaaatgcac agaatatgac cctccttgca ctgattctgg tcaattatat
     1261 aataaagact ttgtattaaa gaacagtatt attaaaaata tagattatat agatgtaaat
     1321 cttaagaatt tatcttgcaa aaaagagttt ttgggaaacg agctttgctc gtttccatct
     1381 gaatgttata acaattcttc ttttttaaat gattctgaag ctggttgttt tgtttctaag
     1441 aaagaatact atgaaacagc tagttttaaa ctaccttgtg ctaatataca tcccgagatt
     1501 gttgcaagaa ccatcaaaga tatatctgaa aataaagaat taaggcattt ctatccatta
     1561 tcagaaaaag atgtagatat gcttaacttc aaagcaaaca ggggatttag cactaacttt
     1621 gtaaaccagt tactattgaa gctatatatc aaatatcctg aaaagaaatt taagaataaa
     1681 tttaccttct taagctatat ggagaaagtg cttgcgagcg aaaaacatca aggaccactt
     1741 gttaatcata caacatttag attcagttgt aatataggtg ctgaagagca gaacatgtta
     1801 gaacatgagc aatatttaag ccacatagag aattcatttg ataccagtaa agaaatgcag
     1861 gtaaagaaga agatagcagg aagatttagc acttccatag cgtattcaat actaactcaa
     1921 gtagagttta agataaatgc caacaacagc tttataactg tattaattcc aagtaaccta
     1981 gctttaagcg agcgacaaat agagatctta agtgagcagc tagaagcagt atatggaatg
     2041 aacggttatt atgtgcagga ggtagaagag atggaggata caagcaatga aagaaatcgg
     2101 agagatgaag aaaaggtaat gctatatcct aaaatcacaa catctgatat tgtgtctaat
     2161 ggtacacatg caggtatttt agcgaaaagt gggggattag atacgatcga agtagataca
     2221 gcatggcatc atatcagaca aggattaatt gaagagttag gagaagctat gtatacagct
     2281 tggtttgaag aagtagtagt aaaggagtgc aatgatactt ctacactaaa gcttacaatg
     2341 ccaacaagat ttatggcgaa ttgggtgcgt aataattact ctcatgtgat acagaggctt
     2401 ggctctagtg caggggttaa gagagtggaa tatggatatt agttaaaaaa ttatagtcaa
     2461 agtaagtgaa aacacagaat caaaaacata agcgaaggta atcctcccta aaaaaatcga
     2521 caagaagagt agaagtttct aataacaaaa aaggagcttc tgtaaaatga ctatatcaaa
     2581 gcatagtgac agccaaatca tgtctatctt aaagcaagca agtagtggtg tacccgtagc
     2641 atcgatactt agagagtaca aaatatcatc atagagatca aggtatggag gtatggattt
     2701 accgatgctt accaagctaa aggaattaga atcggagaat gtccgactta aaaagatgta
     2761 tgctgaggaa aggttaagag ccgataaaac aataaatgat tgctggtcta tggacttcat
     2821 catgcataat agtttagaga atggaagaag atatcgttac atcatgttgt atcaagttag
     2881 gttctacgct gttggctata ctttacgtag gctggattct caccaactgt tccttacgca
     2941 ctttgcttgg cacactggcg gatggactta aatgcaccat taaaaatttt aggttataat
     3001 gctcccatgc aatctatatc ctctgttagt atctgtgcat tatgtatgac ttctatatct
     3061 ggtgtcttat ttattccata aatacgactt ttaattgtat caatatttac atcttcatta
     3121 ctgtgaccaa tccgtatagt catggtgcca ttactatctg tatcactaat atcatcagat
     3181 tccgcatccc aatcccatac ctcgcatcct gaatcatttt cttcatttcc tgaagtatga
     3241 tccgattttg aattagccat ttcccgcact aaatctggat ctagttgtgg gaattctata
     3301 cgttgtagtt tactaaagtg accatcataa taatcagttt catgatatgg ctgttgccct
     3361 gtaagatgaa ttataatatt catctcctta actgttgcag taagtatacg aattccgtac
     3421 agccctatcg cattacaatc aagattaaga tatgtaatct tagtatcctt caatatcttc
     3481 gcgagtgcta ttgcaccagt attgtctaca ttattaaact caagattaag atatgtaatc
     3541 ttagtatcct tcaatatctt cgcaagtgct atgattcctg cagcgtctat actgttgtat
     3601 ccaagattaa gatgtgtaat ttgagtatcc ggcaatatag cagctagttt ttccactgca
     3661 tcatctattg tagtatctcc tacattatta ctacttaaat caagatgtgt aatttgagta
     3721 ttctttaata tagccgccag ctctacagtt ccagtatcgt ttatcgcatt actgctcaga
     3781 ttaagagatg taatatgcat attattcaat atcttagcca gttctctaac tcctatatca
     3841 cctatgtaat tctgtctaag attaagatat gtaatttgag catcctttaa cataggtgtc
     3901 aatattttga tttctgtatc tcctatatta ttattgctta agtcaagata tataatttga
     3961 gtatccttga atatagtcat caattcttct attctaatat tcattatgtt atcatcagaa
     4021 ataaatttta tggtaataat attgatacaa tttttttgtt gagatcttct cttttgagaa
     4081 ctcaagacat cactactaca atttgtgttg tcactattat tctgcaaatg caaattcact
     4141 tctgtgcaaa ataatttgtc ttttttcttg tacccttgga catattgtaa tttcttatta
     4201 aaagtcttac taggaggatt attagtattt tgattatttt gtatgactgc atctatcaat
     4261 aaattcttgt ttatgtaatt taattcataa tctgatttca tttgcatact agaggtagta
     4321 ttagtatatg tatttataca ttttaaataa tattttaggt atgcatgatg atcatttaga
     4381 ttaggatttt tattagaggt attggctatt ttgatttctt gaagctgatt tgtagagagt
     4441 tcaccatcag atgataggtt tttctctgtg tatcgctgtt tctcgagatg ccgttcctta
     4501 atttgtgtat tataactaac tcgcttcttt agcattgata atgaattttt aatactattc
     4561 tgatctgtcc acatattttg tagtgataca tcttgtaatt gtgatgtctt gcctgtatct
     4621 gttgctatat atggttttcc tttactcact aagatcaaag ttttttaatt tatattaact
     4681 atttttgctg tatcaacata atatctagta ttttcgtgat agatagatac atcttgtaat
     4741 tgtgatgtct tgcctgtatc tgttgctata tatggttttc ctttactcac taagatcaaa
     4801 gttttttgat ttatattaac tatttttgct gtatcaacat aatatctagt attttcgtga
     4861 tagatagata catcttgtaa ttgtgatgtc ttgcctgtat ctgttgctat atatggtttt
     4921 cctttactca ctaagatcaa agttttttga tttacattaa ctatttttgc tgtatcaaca
     4981 taatatctag tattttcgtg atagatagat acatcttgtt ttaatgttcg atcgtttggc
     5041 tttatggatc ctattatata tgatattaag ccgtctaacc tatttattct aagatattta
     5101 ggtactatag taggtatact actatattgg tttaatgtgt tgaatataaa tttgtttaat
     5161 atgttatgag taacatcaag attattacag ttttgtaagt tgagtttata ttgcaaatgt
     5221 gatgcagaac cagactgtgc aatgctgtgc atccttctgg tacgtatttg tacttctagc
     5281 ttccgtaaat ctttatctat tattactgta tgtagtgatt gataattatt tttctttggg
     5341 cacttaataa aatctttatt tcgttttgga acatgtgcat aatagtttaa aatagtattt
     5401 aataccttat aacattcatt atcttgtgtt actattactc tgatgccgat aatatcacat
     5461 aagtttttta tttcattaga cttatttact aacttttgtg ctatagaata agtagactta
     5521 actcgtcctg atattgcata tgctacatcc aatctggata aaatatcatg aaatgaatta
     5581 attactttaa taactaactg atctggattt tgatagttta cttttaagaa atcagttata
     5641 aatttgtata acttaggctg taatatttct aaacaaacat tttgtaatac attgttaatt
     5701 ttctctactg ttatttcttt aaataaaggt acgtatatat cttttatctc ttcactcatt
     5761 aagtaatatt ctatatctga tatattgcaa ttaaatatta ttttatgtaa taaataagca
     5821 aatcttatta ataagattct gattgcaata ttaggcttta atgaacaaaa caactgaaac
     5881 gtttcttgta ttgtattaca atatgtattt tgtattcgaa ataattcagc cagtgaaaaa
     5941 aatatcgtag ctatttcttc accaaaatga tatttaatgt gcgttaatgt taagtgattt
     6001 tttagctcag taaaaaataa caaagatgta ataacggatt tagtatcagg atatattgag
     6061 atcagggttt ctgatatttc taatgagtac ttattattat gacaatattt taagagaaac
     6121 ttgatagcct tatcaaattg tgtacaatca aaatgatgat catacctttg aagtattgta
     6181 atgatatgtt gataagtcat gatgtttgat acaacttgag ttagtctctc cgtcaaaatc
     6241 ctacgagccc ttataggtca tagggtttta aggaagtaat agccaaaaat ccataagaaa
     6301 atgaaaggtt tgatatcaaa agcttatggc aataagcaaa aatcgcaatt ggaaataggg
     6361 tattttttat acaacaattt gcaattagga gggtgtcaaa gtctattctc aggagacagt
     6421 agtgggtttg acttatccaa ctattaataa gatttgctta tttattattt aaattgtgtg
     6481 atttacaaac atagttacaa ctaaaatgtc tatttaattc gtaactaatt aagcatgttc
     6541 atagaactgt gttaaactag aaacctcccc caataagaca ctctatatag acgattacta
     6601 cttatttctc aattcttaat ttgcatacct ctcttaactt gacggtgcct tctatatacc
     6661 tctaaaatct tcccttcttt gttttcttgc ggctgcagtt ttgctgccgg taaagtcttg
     6721 atgtttttgc tgatttgctt cataagctct gtcaccacaa cctcgggcat attctatttt
     6781 tgctttagca ttcttatctt ctttggtagt gtgtgcaaag cgagctttta ttttgtttaa
     6841 acgcctcata tcatcagggc ctagctcaat attagcctct ttagcttttt ttcaatacct
     6901 ggttaatttg cccctatatt tatttatatt cttattctat atcttttatt tgttttgctg
     6961 tagtcttttt atcaaaatct tccatcattt tctccgatat ttaagttaac aatatatcta
     7021 ttatcgtaca ccgagtaatt aaaaattaac caatttgtgt tatataaact ttatcacttc
     7081 ttcagcaata tatagaattc tattgcattt attgccaagt tctgtgatat agaggttttg
     7141 tcacgtctat gcattatgct caggatttta cactaaaatt tgagatttta gacgctatga
     7201 cgccattaac atttttaaat tcttaaaagt agctctattc tttaattaga acctaccaat
     7261 caaggttaaa caaaatatta tgataatgat aattaaaaat ttaaagtatt acccataaag
     7321 ttaaggagat gttgtatatt agtctgatat tagtatttat taagtatcat aaagtatact
     7381 ttaagagact tcaaaaactc ttgtcttaat taacgtctct ttatataatt cttgtaaact
     7441 ttaaaagatt ataagacata aatatggcaa cagtaggata tgcgagagtt agttcatcag
     7501 gacagtcgct aagtgtacaa ctagataaat taaaagattg tgataaaatt tttcaagaaa
     7561 agaaatccgg ttttggcggc acaagaagcg tgctaaaaaa tgcattagat tatgtacgtg
     7621 aaggcgatat attcactgtc acaaaactag atagattagc acgctctact gcacatttat
     7681 gcaaaattgc tgagatttta gaacagaaat ctgtagcact taaagttcta gatcaaaata
     7741 tagatactaa agatgcaact ggtcgattaa tatttaatgt gttaggagcg atcggacaat
     7801 ttgaaactga gattagagct gagcgacaaa tggatgggat cttaaaagca aaagagagag
     7861 gcgtgaagtt tggcaagaag aaatacttaa cacatgaaca attaagtgcg ttgaaagaga
     7921 agcgagagca gggtgttaag atcaaaactt taatgcaaga gtttaattta tcaaaagcaa
     7981 ctatttatcg ttatcttgct caggagctta tttaatttct agcatacttt tgcgctcatt
     8041 ttccagtata tataattgaa tttagaacaa taaaaataga atgtaaatta tgtactatac
     8101 tgcattgaaa gatataaagg aaagttgata ttaagattca aaaaagaaat agatttagaa
     8161 gaatttaagt caaggggcga agcccctttg actcaagaat taggctttga gaaggttatt
     8221 gatttcagaa atagataagc cggtaatacg cgaaacctca ggaatagagt aattattaga
     8281 aagcatattt ttagctactt ccatagttct ttcatgtttt ccctcattct taccaatctg
     8341 catgccttga gcaatcccct catcaatata tttatcagca atagttctca taagcccctc
     8401 cccgtctgct ttatttagat gttttgctat gattttagct agctctgctt gtttatctgc
     8461 atctacctta gcatcactat accacaataa ccatttaatg taaatgtatc catttttctt
     8521 atctatttct atactacttt taaacctctc aagtaggctt tgccatagat ttaagatatc
     8581 acgagccttg atatgtttaa gcatatactc catcatacca agatgctttt ttttctctat
     8641 ttcatcatca ctttgttttt gcaaatcaac aagcaagtat tcatctaaca ttagagtttt
     8701 agcagtatta ctatcttcaa ataattccca aaagctcctt ggagcattat aaggtttatc
     8761 atttgcatat actactatag gacatattag aggaagttta tctctttctt gtttgttgtt
     8821 acccttattt gcgtccttat atctttcaca taatagcagc atatactgcc acagtctaaa
     8881 ggcaatccag taatcactac tagactgatg ttctataagc acatatacgt aagctttgtc
     8941 attatctaca ctatcggtgg tactatcttt cacattatca ttttttaaag aaacagagta
     9001 aacaacatca ctgaatctct tttttaaatc ttcagtaaca aagctttcct tttctatttt
     9061 aacactattt agattaatct tgttcttaaa tgatactggc aaataatgct ccagaaactc
     9121 acgagcagca ataggctcgc tcatgacctt tttaaataat tcatcatgtc ttggacgctc
     9181 agaaacaccg ctattttcta actctgtttg ctgttgtttc tgattatgct cttcattagt
     9241 catgcttgtc aatccttata atctcatggt cattgtatgt tctaactctt tctctaggcg
     9301 gggttcttta acttctgctt ttaccttagc aaaggttgat gctacaggct tctcatctac
     9361 aaagcctggt atattatttt gcatcccatg cttcatatat ttaagcgagt atgaatattt
     9421 cttagctctt accatcgcat gctcatcatc taatagctgc tttcaccacg atgctccata
     9481 taatacttct cacatgttgt acttaaagtt ttaagcgcat tatgactatc agaagagtta
     9541 attagtatct cgtgatcctt taatatacca tgtttttggg catacaccat catattatgc
     9601 ataaaaatta cctaccgtta aaacaatcac agtgttaatc agttttttaa aactcagcaa
     9661 atatgacgat gagtggctca gagtagggca tcaactactg ctactgcaaa gacctacaga
     9721 taagcgaaga tgctataggt cagctttatt atgttttaag tcagtaatca aaacccattc
     9781 tgataattac gtagcatatt actttggcgg tatcattatg ttggcttgga agttatgacg
     9841 aagcaataaa gatgtttgat atgagtcttc gctgtaacaa agaagaaagc actgctcttg
     9901 tacatgaagg catcagactt gctacaggaa ataataacag tggtaatggt gatgcccatg
     9961 cagaaatgtt ttttgttaaa taacgagagt ttaacagtga atgaggggcc tagacaagct
    10021 agagaggaaa atcattaaaa aacttcaaag atacaaaata gatggggtag ggaaaattag
    10081 tgcgactaat cacaaacaac gtatcccgag aatgcaccac gagaatgcac cagcaaattg
    10141 ttatgttggg atgataccgc aaaagcaagg cagatatcat gagagcttag cgacttacag
    10201 aaaagcaata tcattaagac ctggggcttc ggtctttgct ttttatattt gcgtaatatc
    10261 aaaggttttg gttggaatca caaacgtgta tacagaatat ataaggaatt agcacttaat
    10321 atgagaataa agtctaagaa aagattcctt agagaaaagc ctgaaaagct tatagtacct
    10381 aaaacaataa atgcttgctg gtctatggac ttcatgcacg atagtttaga gaatggaaga
    10441 agatatagtt tatttaatgt gattgatgac tttaataggg agggtcttgg tattgagatt
    10501 gacttttcgc taccggcaga aagagtcata agggcactag atcaaattgt tgttcattca
    10561 gccaggttaa cctcagcaaa atgcatatat tgaaagatat aataggactg taagatatga
    10621 ttggttgagc cagcatttat tttataatat acaagagtgc aagaggtaca agatcttgcc
    10681 actaaatggc tttggtcata taataacgaa agaccaaaaa ttagctttgg cggcttaact
    10741 ctctaccctt tattaccatt aaaaatgtgg ggattaccat gtagaatata gatgaaaagt
    10801 agcattgcta cttttcatct agaagtgagt aggatatcaa gatccaattg atcttattca
    10861 attgaatttt gctaaataac cgtataaagt ccttagattt tatataaaat atgttattat
    10921 ttcaacgagc aattagcata gaaattcact taatcctaaa atgctagaat catcataatg
    10981 ttgtactatt ggtatataga cagttgcaag tcttggtggt agttgcgggt aatcatagat
    11041 tggtgcacaa ttatcacata ttggtattcc agagtcgctg tcctctatat gtaattgagc
    11101 aagtctatga gaattgacat gactgctctc ttgagtagag ctatcagttg aactcattaa
    11161 ctccattctg tcgtgatcat cagaatgtga gctagaggga ctcattaact ccattctgtc
    11221 gtgatcgtca gaatgtgagc tagagggact cattaactcc attctgtcgt gatcgtcaga
    11281 atgtgagcta gagggactca ttaactccat tctgtcgtga tcgtcagaat gtgagctaga
    11341 gggatttgaa gtatcatatg tagcttttgt atatgtagcc ctcttactaa caatgtctac
    11401 aatagcatac tccgtcccat ctgccgaaga actatcactg taatagattt tagcttttct
    11461 attattaatc tctattagag taggatcact aatattaata tcagcagcag tttccgtttg
    11521 cgccacaggt gttttcttac agtatttatt atacatacaa gttagtaaat atgtaattga
    11581 tacggctgat gctaaaacta acccgcttac gagcatagta ctatcttggc tatgttgttc
    11641 atcgtagtta ctaatatcag tactattggt actattataa tctataactt cattagtata
    11701 gtttaagctt gtattttcgg ttacggttgt aaagaagaag tctagtatag atgaagtggt
    11761 gttattaatt acatcaggtg ttacttcttg cagcatgtgt tttaacttat cagacatata
    11821 ttttataagg aagataccac attttccagt ttttggtgta cgcatagata tatcatgacc
    11881 ttgtagcact accttatgca catttttaat cagtactgac tcatctgtaa gacactgatg
    11941 ttcatacaat aatggagtgt ttaccgggac taaagatttt atattctgtc ccaaagattc
    12001 ttgtatcatt gaatgagctt acaattctaa atatggtacc attgaggtgt tcaacatatg
    12061 ctttgaggcc taaagagttc gtacttttgc tgagcaattc aaaaatattg catgctactt
    12121 ttgtatcgag tgaacaattg tcagtaggga aacatttact agaaataagt tgctgatcca
    12181 taagataata tttgcgatta cgtaacatgt taccaagttt tacaacatca aatgttttat
    12241 tactatcttc acatgtgttg gtattacccc agattgtgcg gaatgtgttt agcaatagtg
    12301 gaaaaatttc attcatttgt atctctctag ttttattaaa aaattattta ttagtggtat
    12361 tgattgatat tgccactatc ttgccctggc ccatcatata accttttttc attttatcaa
    12421 ttagattatg gaaagatatt atgaattatc acacaaagat aaccaattat agtatttagg
    12481 caatataaag tagtatattg aatagcttaa gggtacgaac ttaataaatt ataaatatta
    12541 gattatctta tctaatatta attaggtgtt tgagttaggt ttagagcatt taaggtattt
    12601 ttagtttttg gtggcacttc ttctttagtt actaaacttg ctgaagcccc ctcaagatta
    12661 aatctttgtg ctccttcaat aaggagtttt ttatatcccg tgagcatgag ttctttaagt
    12721 ctcttgatgg caatcttaaa tatgcagagc agtatgatag tagtttatta tctgcagtat
    12781 caaatgctaa gactatcgag caagataagc taatcactaa gatgaggatt ggttattatg
    12841 atctgcattg tcagcattgc acgcttgatc tacaaaactc gcaacattag ggtcataaga
    12901 tatgtgaact aatcttgcag ctttaggttt ttttatgatg catgaggttt ttgaagcaac
    12961 tcttgctggt tgctagaatt atgaaagcca gcggggccta aagtgttgcg gggactagaa
    13021 aaatgagcag atgttactct actaattatt gccatcacat acattatgtg ttatatttat
    13081 tgtgacctcg tatctattta ggggtgactt taatcaccag taaacactct ccttgtccaa
    13141 aatttgagtg tttactggtt tttcttttta taagatagta ttgtacttta ttatgcaatc
    13201 cactacctca tactgctact ttattaaata tattttggtg tgtcaagaaa atagtttctg
    13261 gtattcagaa actatttgta tgatattttg agttatttat ggatatttca ctaaggatac
    13321 aaaaattttt aagtcaaaaa attaaaactt ataaaataca acaaaaagat ttggtattag
    13381 gaacatcttt atcgcgatct actattagca aactcctaaa cgcaatttta cttaatccta
    13441 atatcatcac tattcttaaa attgcaacat tctttgaatg tgatatagat gaagtacttg
    13501 gtcgcgcaaa atttataaaa aatacaaaaa aatatcaatt atatgtatct ttaactttaa
    13561 atgatattaa taatcattta ctctcttttc ttaaaacaaa aatacagcaa cttaacatta
    13621 cagagtatat attggaaaaa aattgcagag taggtagtag tactattact cattttatta
    13681 atacaaatag tgataataga attttaagta ctaaagttat cgtaaaactg gcagattatt
    13741 ttcaaatctc tatagatgaa atgattggta ggaccaaaat ataaacatac atattcctat
    13801 atgtttatat gctcatatga tttgtactac actaaaattt agttataagt ctgatcaaga
    13861 aacgtgacga atagtatttt atcctgctta acattaagta tccttgcttt aataaacaaa
    13921 aacattaagt taagacatat aagcatatat atgtctatat actcttttct acagcttcta
    13981 taattatttc agtcattgtt acctccctcc tagccgcctc gatttttaat ttcttatgca
    14041 atttttctgg taaaaagata gtcgttctct tatgtttttg atcttgttgt gcatgtttta
    14101 tattacccga cacccatgca tcaataaatt gagtagtatt tttttgtacc ggttttttgg
    14161 ggaactcaat tctttttcct gtcatgacct gttcaattag ttatattttt ctaaaatttc
    14221 atttgttaaa tctgttattt ctctaacggc tagattgtct ctattatgct cttccataac
    14281 tgtggaacca atagctgctg tttctgcata tgccactctc tgacaaatat gtgtttgtaa
    14341 aatatccata ccgtaatgat ctaacgcttg ttccacatct cgaccaatag cagtattgga
    14401 tattttccta ttaattaaaa aggcggactt tatatttttt cttccttcta atggttgaga
    14461 tacttctttt ataaggctaa ccacttcatt agctgcccat atatcataag gtgacggttg
    14521 cactggcatt actaccaggt cactagtaac tattgcagac ttagcaacat catatatcct
    14581 tggtggtcca tcaataatta tatgatcata attcttaacc aattttgata cctctttatg
    14641 tattattggt tttgtgagcc caactacagt gaataaactt tcttttctac gaattgcaac
    14701 ccaatctagg gaactatttt gtggatccgc atctattaaa agcacttttt gcttttttag
    14761 tgatagacat gttgcaacat taattgaaag tgtagtctta cctacacctc ctttttgatt
    14821 caagaaagat aaaatcataa taacattatt tattttttat acgataatat aaatatataa
    14881 acatacatat gtcaatatgt ttatattaaa ttgtaaaaac atacatatat attaacatat
    14941 atatgttatg tgctctgatt ttaaaataat tattttttat gcgtgaaata attattctta
    15001 ttgacatgtg tacaaaatat gtttaattat gattataatt catttatctc aatggcttta
    15061 tgctgaagaa aataaacgta aaaaggatat ctttagatat tccagagcat attatagaaa
    15121 agattgataa aatttgtgct gaaaacttta tcacgcgcag aaagtggttt atagacgctg
    15181 caaatgataa actcgagaag tatgaattaa ataaaataga tatgatagtg aaaaaataaa
    15241 ctacaggtgc taagttctca aaatagctaa aaactcaaca ccttga
//
